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Rho亚家族与消化系统恶性肿瘤侵袭及转移的关系 被引量：1

Advance in Relationship of Rho Subfamily Proteins to Invasiveness and Metastasis of Digestive Cancer
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摘要 Rho亚家族是一类小分子G蛋白,在细胞信号转导及细胞运动中起重要作用,参与恶性肿瘤细胞侵袭转移各个过程中。Rho蛋白在许多消化系统恶性肿瘤中表达增高,可能成为一种新的肿瘤标志物,可以用来判断肿瘤侵袭转移能力,并可能成为肿瘤治疗新的靶点。本文就Rho亚家族与消化系统恶性肿瘤侵袭、转移的关系研究进展进行综述。 Rho subfamily is a kind of G proteins,which plays an important role in cell signal transduction and cell movement.Rho subfamily proteins,which express increasedly in many digestive cancers,may be a new tumor marker for determination of the ability of tumor invasiveness and metastasis and become a new target for cancer therapy.This paper reviews the relationship of Rho subfamily proteins to the invasiveness and metastasis of digestive system cancers.
作者 田小林 蒋志庆
机构地区 桂林医学院附属医院胃肠外科
出处 《中国全科医学》 CAS CSCD 北大核心 2011年第9期1038-1041,共4页 Chinese General Practice
关键词 Rho亚家族 消化系统肿瘤 肿瘤浸润 肿瘤转移 Rho subfamily Digestive system neoplasms Neoplasm invasiveness Neoplasm metastasis
分类号 R735 [医药卫生—肿瘤]
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中国全科医学
2011年 第9期

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