摘要
目的探讨非小细胞肺癌(NSCLC)根治术后发展到Ⅲ、Ⅳ期患者中医证候的分布规律。方法采用流行病学调查方法进行临床观察,根据预先设计的观察表和临床证候诊断标准,按纳入标准严格选择病例,以先辨单证,再辨复证的方法进行辨证分型。结果共收集到117例非小细胞肺癌(NSCLC)根治术后Ⅲ、Ⅳ期患者,不同中医证候之间差异有统计学意义(P<0.01),单证中气虚证占总病例数的67.52%,其次分别为血瘀证占47.86%,痰湿证占35.90%;复证中,气虚血瘀证占41.88%、气虚痰湿证占19.66%;3个或以上的单证相兼以气虚痰湿血瘀证(占23.77%)、气虚血瘀气滞证(占17.95%)常见。结论非小细胞肺癌(NSCLC)根治术后发展到Ⅲ、Ⅳ期证候分布复杂,单证少,复证多,且多虚实互见,最常见的虚证为气虚证、阴虚证,在虚证的基础上容易合并血瘀证、痰湿或痰热证、气滞证等兼夹证,总以气虚、血瘀、痰湿相兼多见。
Objective To investigate the TCM syndrome distribution law in Ⅲ and Ⅳ periods of patients with non-small cell lung cancer（NSCLC） after curative resection.Methods The methods of cross-sectional investigation was used to observe the distribution law with pre-designed forms and diagnostic criteria for clinical syndromes,the patients were selected with the inclusion criteria,and the syndromes were differentiated in different types according to single syndrome firstly and then complex.Results Total of 117 patients with NSCLC after curative resection in III and IV period were collected,the differences between the different TCM syndromes were significantly different（P〈0.01）,Qi weakness syndrome was 67.52% in all single syndromes,in which,the blood stasis syndrome was 47.86% and damp-phlegm 35.90%;in the complex syndromes,the Qi-deficiency with blood stasis was 41.88%,Qi-deficiency with damp-phlegm 19.66%;in complex three or more single syndromes,the common syndromes were companied with Qi-deficiency,damp-phlegm and blood stasis（23.77%） and with Qi-deficiency,blood stasis,and Qi-stagnation（17.95%）.Conclusion When the NSCLC after curative resection developed into Ⅲ and Ⅳ periods,the syndromes distribution will be complicated,the single syndrome less and the complex more,and companied with deficiency and excess are common.The most common are the Qi-deficiency and Yin-deficiency;and the Yin-deficiency is easily companied with blood stasis,phlegm-heat,damp-phlegm and so on,while the Qi-deficiency and blood stasis,and phlegm retention syndrome can see more.
出处
《湖南中医药大学学报》
CAS
2010年第11期48-50,共3页
Journal of Hunan University of Chinese Medicine
基金
湖南省教育厅项目(05A033
07C488)
湖南省高校创新平台开放基金项目(09k058)
关键词
非小细胞肺癌根治术后
证候分布
单证复证
Non-small cell lung cancer after radical mastectomy
Syndromes distribution
haplo-syndrome
amb-syndrome
