摘要
目的了解近6年来就诊于我院的胃癌患者流行病学及临床病理资料的特点,为疾病的诊断与评估提供帮助。方法将2004年1月至2009年12月期间于我院进行手术治疗的958例胃癌患者作为研究对象,对其一般资料、肿瘤病理类型、发生部位、临床分期等进行回顾性分析。结果 958例胃癌患者中,男697例（72.8%）,女261例（27.2%）。年龄26~91岁,平均62.6岁;高发年龄为46~65岁组,占49.4%（473/958）,其后依次为≥66岁组及≤45岁组,分别为42.3%（405/958）和8.3%（80/958）。病理的大体分型上,BorrmannⅡ型占大多数（70.1%）;病理类型以腺癌居多,占82.3%,印戒细胞癌占7.8%;分化程度以低分化为主,占46.9%。发生部位以贲门居多,占53.0%。TNM临床分期中以Ⅲ期为主,占47.4%。结论①胃癌多见于中老年男性患者,以贲门部低分化腺癌多见,贲门癌发病率明显高于胃窦癌;②在胃癌患者中,恶性程度较高的低分化、印戒细胞癌中所占比例最高者为相对较年轻的患者（≤45岁组）;③行手术治疗的大部分为中晚期患者,胃癌的早期诊断有待进一步提高。
Objective To investigate the clinicopathologic and epidemiological characteristics of patients with gastric cancer at our hospital in the past six years.Methods A total of 958 patients with gastric cancer were selected from January 2004 to December 2009 and clinicopathologic characteristics such as basic data,pathological type,tumor location,and TNM stage were retrospectively analyzed.Results Of the 958 patients,697 cases（72.8%） were male and 261 cases（27.2%） were female,and the age ranged from 26 to 91 years old（mean 62.6 years old）.The occurrence rate of gastric cancer was higher in the patients of 46-65 years old（49.4%,473/958） than that in the patients of ≥66 years old（42.3%,405/958） and ≤45 years old（8.3%,80/958）.Regarding pathologic type,the majority of advanced gastric cancers（70.1%） were Borrmann Ⅱ,the adenocarcinoma and signet-ring cell carcinoma accounted for 82.3% and 7.8%,respectively.The cancer of gastric cardia accounted for 53.0%.Stage-stratified analysis revealed that the majority of gastric cancers（47.4%） were stage Ⅲ.Conclusion ①A prevalence of gastric cancer is found in middle,elderly male patients.Poorly differentiated adenocarcinoma in cardia is prominent.②Patients with high malignant ganstrie cancer are younger.③The majority of patients who underwent the surgical treatments have advanced or metastatic tumor,therefore it is necessary to improve the early diagnosis of gastric cancer.
出处
《中国普外基础与临床杂志》
CAS
2011年第2期153-158,共6页
Chinese Journal of Bases and Clinics In General Surgery
基金
南京市医学科技发展资金资助项目(项目编号:YKK09066)~~
关键词
胃癌
临床病理特点
流行病学
发病率
手术治疗
Gastric cancer
Clinicopathologic characteristics
Epidemiology
Incidence
Surgical treatment
