摘要
目的探讨机械通气联合肺表面活性物质(固尔苏)治疗新生儿呼吸窘迫综合征(NRDS)的临床疗效。方法将72例确诊为NRDS患儿分为两组,对照组36例给予机械通气治疗,治疗组36例在机械通气治疗基础上加用固尔苏治疗。比较两组治疗后的血气分析结果及临床疗效。结果治疗组在用药1、12、24 h后PaO_2明显提高,PaCO_2下降,pH上升,与对照组比较有显著差异(P<0.05)。治疗组总有效率明显高于对照组(P<0.05)。结论呼吸机联合肺表面活性物质能有效改善NRDS患儿肺通气、换气功能,临床疗效满意。
Objective To explore the clinical effect of the mechanical ventilation and the pulminary surfactant （PS） in the treatment of the neonatal respiratory distress syndrome （NRDS）. Methods 72 cases of the NRDS were divided into two groups. Only mechanical ventilation was given in control group. While in the treatment group, apart from the mechanical ventilation, the pulmonary surfactant was added and then compared the blood gas analysis and the clinical effect. Results In the treatment group, 1 h,2 h and 24 h later, PaO2 improved obviously, PaCO2 going down but pH going up （P 〈0. 05）. Compared with the control group, the efficient rate was higher in the treatment group （ P 〈 0.05 ）. Conclusion Breathing machine combined with the pulminary suffaetant can improve the NRDS＇ lung ventilation and dysfunction of ventilation. The clinical effect is satisfing.
出处
《中国医学创新》
CAS
2011年第7期42-43,共2页
Medical Innovation of China
关键词
呼吸窘迫综合征
新生儿
肺表面活性物质
机械通气
Neonatal respiratory distress syndrome（NRDS）
Newborns
Pulminary surfaetant（IS）
Mechanical Ventilation
