摘要
对某石棉制品厂接触石棉工人进行了剂量-反应关系的调查研究。各作业场所石棉粉尘的各时期的重量浓度用另文所介绍的转换方法换算成计数浓度。对工人的职业史作了详细记录。石棉肺病例根据职业史及胸片诊断。患者的接触剂量系用换算得的计数浓度乘其接触时间,并累加至诊断为Ⅰ期石棉肺之日止,其余工人的接触剂量则加至1982年9月止。用寿命表法建立了石棉纤维计数浓度的剂量-反应关系。据此,可预测3％的石棉肺患病率时,接触剂量相应为43根·年,以工人一生工作35年计,相当于空气中石棉纤维浓度1.22根/ml。建议以1.2根/ml为车间空气中石棉尘的计数浓度卫生标准。
Dose response relationship of workers in a chrysotile product factory was studied. The pgst gravimetric dust concentration records of different workplaces were converted into fibre counting concentration according to conversion factors which were worked out by simultaneous sampling with the two method in a previous study. Occupational history of each worker was recorded in detail. Asbestosis cases were diagnosed on the basis of their chest radiographs and occupational history. The exposure level was estimated by multiplying the couverted fibre counting concentration by the time period the worker exposed to that concentratiou and summing them up to the diagnose date for those asbestosis patients, and up to September 1982 for the rest of workers. Dose response relationship of fibre years exposed to vs. cumulated prevalence of asbestosis was established by the method of life table based on these data. The predicted 3% prevalence of asbestosis corresponds to 40f/yr exposure. Considering a worker can work for 35 years, these doses are commensurate with the dust concentration of 1.22f/ml. The recommendation that setting 1.2 f/ml as the maximum alloawble concentration of airborne asbestos dust for the workplace is suggested.
出处
《工业卫生与职业病》
CAS
CSCD
1989年第6期335-338,共4页
Industrial Health and Occupational Diseases
关键词
石棉
石棉肺
接尘量
剂量
asbetos
asbestos exposure
absestosis
dose-response relationship
chrysotile
