摘要
目的:了解常州市2004～2009年细菌性痢疾流行病学特征和病原菌耐药性,为预防控制细菌性痢疾提供科学依据。方法:对常州市2004～2009年的细菌性痢疾网络直报资料和病原学监测结果进行描述性分析。结果:常州市2004～2009年共报告细菌性痢疾8 096例,年均发病率为35.26/10万。全年均可发病,具有明显的季节性,7～9月为发病高峰期。市区发病率高于县级市、男性发病率高于女性,存在统计学差异;其中0～4岁及20～39岁组报告发病比例最高。职业分布以散居儿童、工人、农民和学生为主。鉴定志贺菌113株,共检出102株福氏志贺氏菌和11株宋内志贺氏菌。两种志贺菌均存在多重耐药性,对氨苄西林、复方新诺明和萘啶酸的耐药率较高。结论:常州市2004～2009年细菌性痢疾的发病率总体呈逐年下降趋势,但仍维持一定的发病率,防治不容忽视,提示应加强对重点人群的健康教育工作及疫情动态监测工作。
Objective： To analyze the epidemiological feature of bacillary dysentery and the drug resistance of this pathogenic bacterium in Changzhou city from 2004 to 2009.Methods：Reported data of bacillary dysentery from 2004 to 2009 and pathogens detected through laboratory tests were analyzed by descriptive epidemiological method.Results：A total of 8096 cases of bacillary dysentery was reported during this period,and the average incidence was 35.26/100000.The disease can occur throughout all the year with an obvious seasonal trend,and the peak period for bacillary dysentery was July to September.The incidence of bacillary dysentery in urban areas was higher than that of two county-level cities.The incidence in males was higher than that in females,and the highest incidence rate was found in people of 0-to 4-year-old and 20-to 39-year-old.The reported data also showed that bacillary dysentery might occur in all different kinds of occupation,but most were scattered inhabiting children,workers and farmers.Total of 102 strains of Shigella flexneri and 11 strains of Shigella sonnei were detected in the laboratory.Both strains had high resistance to ampicillin,sinomin compositea and nalidixic acid.Conclusion：The incidence of bacillary dysentery in Changzhou city was gradually declining from 2004 to 2009,however,the prevention and control can not be ignored because the incidence of bacillary dysentery still maintains a certain level.In order to control the incidence of bacillary dysentery in Changzhou city,the health education in focus groups and the epidemic dynamic monitoring need to be enhanced in our future work.
出处
《南京医科大学学报（自然科学版）》
CAS
CSCD
北大核心
2011年第2期274-278,共5页
Journal of Nanjing Medical University(Natural Sciences)
关键词
细菌性痢疾
流行病学
志贺菌属
耐药性
bacillary dysentery epidemiology Shigella drug resistance
