摘要
目的评价美沙拉嗪与柳氮磺吡啶治疗溃疡性结肠炎的临床疗效。方法将80例溃疡性结肠炎患者随机分为治疗组和对照组,每组40例。治疗组给予美沙拉嗪进行治疗,对照组给予柳氮磺胺吡啶治疗,疗程均为8周。观察比较两组的疗效和不良反应发生情况。结果治疗组总有效率(85.0%)高于对照组的(62.5%),差异有显著性(P<0.05);治疗组不良反应发生率(10.0%)明显低于对照组的(27.5%),两组比较差异有显著性(P<0.05)。结论柳氮磺吡啶结肠溶胶囊治疗溃疡性结肠炎疗效确切,不良反应发生率低。
Objective To evaluate the effect of mesalazine with sulfasalazine for ulcerative colitis patients.Methods 80 patients with ulcerative colitis were randomly divided into treatment group and control group,40 patients in each group.The treatment group received sulfasalazine for treatment,control group received mesalazine treatment,a course of 8 weeks.The efficacy and adverse events of the two groups were observed.Results The total effective rate of treatment group was 85.0% compared with control group（62.5%）;adverse reaction rate of the treatment group（10.0%） was significantly lower than the control group（27.5%）,the difference was statistically significant（P0.05）.Conclusion Enteric-coated capsules sulfasalazine is effective in treatment of ulcerative colitis,a low incidence of adverse reactions.
出处
《当代医学》
2011年第4期138-139,共2页
Contemporary Medicine
