摘要
目的：探讨左炔诺孕酮炔雌醇对多次人工流产后宫腔粘连的预防作用。方法：2007年1月-2008年12月我院妇产科行第三次人工流产孕妇87例,随机分为研究组（A组,41例）和对照组（B组,46例）,A组在人工流产后当晚开始服用左炔诺孕酮炔雌醇（三相）片治疗,B组仅进行口头避孕咨询。随访和观察术后阴道流血持续时间、人流术后月经复潮时间和量的变化、腹痛症状、宫腔镜检查（术后3月）宫腔粘连有无及其程度和乳腺彩超检查。并对上述监测指标进行比较分析。结果：A组术后阴道流血持续时间、月经复潮时间均短于B组;A组月经复潮量减少和腹痛比率低于B组（P〈0.05）。3个月后宫腔镜检查A组宫腔轻度粘连比率、中度粘连比率均低于B组（P〈0.05）。乳腺彩超随访A组无乳腺增生。结论：左炔诺孕酮炔雌醇对多次人工流产后宫腔粘连具有预防作用。
Objective：To study the preventive effect of levonorgestrel ethinyl estradiol on intrauterine adhesions after several times of abortion.Methods：87 cases of third time abortion were selected from January 2007 to December 2008 in our hospital,and were randomly divided into study group（group A,41 cases） and control group（group B,46 cases）.Group A took levonorgestrel ethinyl estradiol（three phase） tablets in the evening after abortion,while group B only received oral contraceptive counseling.Postoperative follow-up was conducted.The duration of vaginal bleeding,changes in the recovery time and amount of menstrual flow,abdominal pain,intrauterine adhesions and extent detected by hysteroscopy in postoperative 3 months and the breast ultrasonography examination were monitored and recorded.The above monitoring indicators were comparatively analyzed.Results：The postoperative vaginal bleeding duration,recovery time of menstruation all were shorter than those in the group B.The rate of amount reduce of recovery menstruation and abdominal pain in group A was lower than that in group B（P0.05）.The rate of mild and moderate intrauterine adhesions detected by hysteroscopy in postoperative 3 months in group A was lower than that in group B（P0.05）.Breast color ultrasound follow-up showed no proliferation of mammary gland in group A.Conclusion：Levonorgestrel ethinyl estradiol has the preventive effect on intrauterine adhesions after several times of induced abortions.
出处
《现代医药卫生》
2011年第3期363-364,共2页
Journal of Modern Medicine & Health
关键词
左炔诺孕酮炔雌醇
人工流产
宫腔粘连
Levonorgestrel ethinyl estradiol
Abortion
Intrauterine adhesions
