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立普妥对急性脑梗死患者血清高敏C反应蛋白的影响 被引量:1

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摘要 目的:观察立普妥(阿托法他汀)治疗急性脑梗死患者血清高敏C反应蛋白(hs-CRP)水平的变化,以了解立普妥的非调脂作用。方法:选择120例急性脑梗死患者随机分为常规治疗组(未服任何调脂药),立普妥治疗组(服立普妥20 mg/d)各60例,应用放射免疫比浊法检测治疗前、治疗后7d、14d的血清hs-CRP水平变化,并对神经功能缺损程度进行标准评分。结果:两组hs-CRP水平在梗死后7d最高,随后逐渐降低。治疗组在治疗前、治疗后14d血清hs-CRP水平和治疗前、治疗后7d的神经功能缺损评分与对照组患者比较差异无统计学意义;治疗后7d治疗组hs-CRP水平低于对照组,14d治疗组神经功能缺损评分与对照组比较差异有统计学意义。结论:立普妥在急性脑梗死患者的治疗中可以降低患者血清hs-CRP水平,有利于减轻炎症反应,改善脑梗死部位缺血缺氧和神经功能缺损。
出处 《陕西医学杂志》 CAS 2010年第11期1524-1526,共3页 Shaanxi Medical Journal
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参考文献7

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