摘要
目的探讨以副肿瘤综合征为首发表现的肺癌的临床特征及误诊原因,以提高鉴别诊断能力。方法回顾性分析21例经病理和细胞学检查确诊的、以神经副癌综合征为首发症状的原发性肺癌病人的临床资料。结果以神经副癌综合征为首发症状的原发性肺癌病人占同期肺癌住院人数的2.27%(21/927)。误诊为肌无力综合征9例,小脑梗死4例,脑干梗死1例,多发性周围神经炎3例,脊髓炎2例,首诊误诊率为88.1%(19/21)。结论对有神经副癌综合征且年龄在45岁以上病人,应寻找有无隐匿性肺癌病灶,以减少肺癌的误(漏)诊率。
Objective To explore the clinical characteristics and misdiagnosis of lung cancer with neurological paraneoplastic syndrome（NPS） as initial symptom to improve the differential diagnosis.Methods The clinical data of lung cancer patients with NPS as initial symptom confirmed by pathology or cytology were analyzed,retrospectively.Results Of the hospitalized patients with NPS as initial symptom was accounted for 2.27% of lung cancer（21/927）,nine cases were misdiagnosed as myasthenia syndrome,four cases as cerebellar infarction,one case as brainstem infarction,three cases as peripheral neuritis,two cases as myelitis.All the cases were eventually diagnosed as lung cancer.The misdiagnosis rate was 88.1%（19/21） at first visit.Conclusion For patients over 45 years old with NPS,an investigation is required in order to find the possibility of concealed lung cancer and decrease its misdiagnosis.
出处
《西部医学》
2010年第10期1815-1816,共2页
Medical Journal of West China
关键词
副肿瘤综合征
神经系统
肺肿瘤
诊断
Neurological paraneoplastic syndrome
Nervous system
Lung cancer
Diagnosis
