摘要
目的为介入法建立犬房间隔缺损(房缺)模型提供相关的应用解剖资料,分析DSA下建立犬房缺模型的操作要点。方法解剖测量15只(雄9,雌6)健康成年杂交犬心脏标本,得出犬房间隔的相关解剖参数;分析5只活体犬心脏三维CT结果,根据获得的透照体位及角度对20只犬进行房间隔穿刺。结果房间隔长(17.8±4.3)mm,宽(14.5±3.8)mm,卵圆窝长(11.2±2.7)mm,宽(8.7±1.9)mm。卵圆窝中点距冠状窦口中点(7.2±1.3)mm;距膜性房间隔中点(9.9±1.5)mm;距右房室瓣隔侧瓣中点(13.6±3.1)mm和距主动脉隆凸底部的中点(12.1±2.3)mm。卵圆窝中点距左房室瓣前瓣中点距离为(11.3±1.9)mm。房间隔平面与矢状面成角15°±5°,与冠状面成角75°±5°,采用右前斜75°±5°行犬房间隔穿刺,20只犬中18只成功建立房缺模型,1只因心脏压塞死亡,1只因误穿入左室死亡。结论建立犬房缺模型应该根据犬房间隔解剖特点和空间位置,来把握DSA下房间隔穿刺的操作要点。
Objective To provide the relevant applied anatomic information for the preparation of atrial septal defect （ASD） model with transcatheter management in canine,and to discuss the technical points in making ASD model under DSA guidance. Methods Anatomical measurements of the heart specimens,which were obtained from 15 healthy adult hybrid dogs （9 males and 6 females）,were performed,from which the relevant anatomic parameters of the atrial septum were calculated. Cardiac 3D reconstruction with 64-sliced spiral CT scan was carried out in 5 dogs and the results were analyzed. According to the trans-illuminated position and angle obtained from 3D reconstruction images both the puncturing of the atrial septum with Brokenbrough needle and the balloon dilatation under fluoroscopic guidance were conducted in 20 dogs （body weight 17 -22 kg） to prepare ASD model. Results The length and the width of the interauricular septum were （17.8 ± 4.3） mm and （14.5 ± 3.8） mm,respectively. The oval fossa was （11.2 ± 2.7） mm long and （8.7±1.9） mm wide. The distance from the central point of oval fossa to the central point of the orifice of coronary sinus was （7.2 ± 1.3） mm,which was （9.9 ± 1.5） mm to the center of the membranous atrial septum,（13.6 ± 3.1） mm to the middle point of septal tricuspid valve,（12.1 ± 2.3） mm to the central point of the bottom of aortic eminence and （11.3 ± 1.9） mm to the middle point of anterior bicuspid valve. The angle between atrial septal plane and sagittal plane was 15° ± 5°,and the angle between atrial septal plane and coronal plane was 75° ± 5°. Thus,the puncture of the interauricular septum was carried out with the dog in right anterior oblique position at 75° ± 5°. Of the total 20 dogs,ASD model was successfully established in 18,failure of the puncturing occurred in the remaining two,of which one died of cardiac tamponade after the procedure and the other one died of mistakenly puncturing into the left ventricle. Conclusion When making preparation of atrial septal defect model in dog it is very important to familiar with the anatomical characteristics of its heart and to grasp technical points in order to obtain a successful puncturing.
出处
《介入放射学杂志》
CSCD
北大核心
2010年第8期635-638,共4页
Journal of Interventional Radiology
基金
上海市科委医学引导类项目(编号:10411960200)
关键词
房间隔缺损
应用解剖
介入疗法
犬
atrial septal defect
applied anatomy
interventional management
canine
animal model
