4David KS, Alan BW. Liver fibrosis and inflammation. A review [J].Annals of Hepatol,2003,2:159-163.
5Mehra A, Wrana JI.TGF-beta and the Smad signal trans duction pathway[J]. Biochem Cell Biol,2002,80(5):605-622.
6Wells RG,Fibrogenesis V. TGF-beta signaling pathways[J]. Am J Physiol Gastrointest Liver physiol, 2000, 279:G845-G850.
7Bronfenmajer S, Schaffner F, Popper H. Fat-storing cells(lipocytes) in human liver [J]. Arch Pathol, 1966, 82:447-453.
8Neubauer K, Knittel T, Aurisch S, et al. Glial fibrillary acidic proteina cell type specific marker for Ito cells in vivo and in vitro[J]. Hepatol, 1996,24:719-730.
9Niki T, De Bleser PJ, Xu GV, et al.Compafison of glial fibrillary acidic protein and desmin staining in normal and CCl4-indueed fibrotic rat livers[J].Hepatology,1996,23:1538-1545.
10Redale JP, Murphy G, Hembry RM, et al. Human hepatic lipocytes synthesize tissue inhibitor of metalloproteinases-1. Implications for regulation of matrix degradation in liver[J].Clin Invest,1992, 90:282-287.
4Swann K, Saunders C M, Rogers NT, et al. PLCzeta (zeta) :a sperm protein that triggers Ca2： oscillations and egg activation in mam- mals[J]. Semin Cell Dev Biol, 2006,17 (2) :264-273.
5Zhou Y, Wing MR, Sondek J, et al. Molecular cloning and char- acterization of PLC-eta2[J]. Biochem J, 2005,391 (Pt3) :667-676.
6Kouchi Z, Shikano T,Nakamura Y,et al. The role of EF-hand domains and C2 domain in regulation of enzymatic activity of pho- spholipase Czeta[J]. J Biol Chem, 2005,280 (22) : 21015-21021.
7Ye K, Aghdasi B, Luo HR, et al. Phospholipase C gamma 1 is a physiological guanine nucleotide exchange factor for the nuclear GTPase PIKE[J]. Nature, 2002,415 (6871 ) : 541-544.
8Chandrasekharan NV, Dai H, Roos KL, et al. COX-3, a cyclooxy- genase-1 variant inhibited by acetaminophen and other analgesic/ antipyretic drugs : cloning, structure, and expression[J]. Proc Natl Acad Sci USA. 2002.99 (21 ：, 13926-13931.
9Giannitrapani L, Ingrao S, Soresi M, et al. Cyclooxygenase-2 ex- pression in chronic liver diseases and hepatocellular carcinoma : an immunohistochemical study[J]. Ann NY Acad Sci, 2009,1155 : 293 -299.
10Yang JI, Yoon JH, Bang YJ, et al. Synergistic antifibrotic efficacy of statin and protein kinase C inhibitor in hepatic fibrosis[J]. Am J Physiol Gastrointest Liver Physiol, 2010,298 ( 1 ) : G 126-132.
