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术中MRI监测下行胶质母细胞瘤扩大全切除术的临床研究 被引量:6

Clinical Study in Expanded Resection of Glioblastomas Aided by Intraoperative Magnetic Resonance Imaging
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摘要 目的:观察胶质母细胞瘤扩大全切除的疗效。方法:对75例胶质母细胞瘤患者采用术中MRI监测下进行扩大全切除、全切除和部分切除手术,观察患者中位生存期和2年生存率。结果:扩大全切除患者中20/31例(64.52%)生存期超过2年,中位生存期为24.71个月;全切除患者中6/18例(33.33%)生存期超过2年,中位生存期为17.28个月;而部分切除患者中无一例生存期超过2年,中位生存期为11.15个月。结论:胶质母细胞瘤扩大全切除较全切除和部分切除可明显延长患者的术后生存期,术中MRI监测是保证全切除和扩大全切除的重要方法。 Aim: To investigate the efficiency of expanded resection of glioblastoma. Methods: Using intraoperative MRI monitoring technology, the 75 patients with glioblastoma were performed expanded resection, total resection, or partial resection, and their median survival time and 2-years survival rate were observed. Results: 64.52% (20/31) of patients with expanded resection have survived more than two years and the median survival was 24.71 months; 33.33% (6/18) of patients with total resection have survived more than two years and the median survival time was 17.28 months; none of patients with partial resection survived more than two years and the median survival time was 11.15 months. Conclusion: Compared with total resection and partial resection, expanded resection significantly prolonged the survival time of patients. Intraoperative MRI was an important monitoring method to ensure total removal and expanded resection.
出处 《中国临床神经科学》 2010年第4期381-384,共4页 Chinese Journal of Clinical Neurosciences
关键词 胶质母细胞瘤 术中磁共振 预后 glioblastoma intraoperative magnetic resonance imaging prognosis
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参考文献12

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