摘要
应用参元丹煎剂治疗不稳定心绞痛(UA,血瘀证)113例,总有效率为90.3％,对各种证候及各种类型的UA均有良好疗效。患者血浆一氧化氮(NO)及组织型纤溶酶原激活物(t—PA)低于正常人水平,治疗后有所恢复;患者血浆内皮素(ET)水平未见异常,治疗未见影响。提示参元丹的部分疗效机理可能是通过调整血浆NO、t—PA水平,促进血管内皮修复,降低血管张力,减少不稳定血栓,从而改善患者冠状动脉供血来实现的。
This therapy, with a total effective rate of 90%, was satisfactory for all syndromes and various kinds of UA. Those cases with plasmal NO and t -PA lower than normal recovered to certain extent after the treatment. But there was no effect on plasmal ET after treatment, indicating that the mechanism of Shen - yuan - dan may be partially due to the repair of vessel endothelium, lowering of vessel tension, decrease of unstable thrombus through the regulation of plasma NO, t -PA level, hence, the improvement of coronary blood supply.
出处
《中医杂志》
CSCD
北大核心
1999年第4期219-221,共3页
Journal of Traditional Chinese Medicine
