摘要
目的探讨应用三维超声体积自动测量(VOCAL)技术测量胎儿肺体积的可行性及超声肺重比(UFLB)对胎儿肺发育不良(PH)的诊断价值。方法选取经产前超声检查诊断为先天性发育异常且孕妇选择引产并同意进行尸检的胎儿35胎,胎龄16～36周。应用VOCAL技术获得胎儿肺体积,采用二维超声测得的生物参数经Hadlock方程系统自动生成胎儿质量,进而获得UFLB。将应用VOCAL技术测得的胎儿肺体积与尸检后实测的肺体积进行比较,并评价UFLB对PH的诊断价值。结果应用VOCAL技术测得的胎儿肺体积与实测的肺体积之间的差值为(-0.81±1.77)cm3。应用UFLB诊断胎儿PH的敏感度为83.33%,特异度为95.65%,阳性预测值为90.91%,阴性预测值为91.67%,诊断准确率为91.43%。结论应用VOCAL技术可准确评估胎儿肺体积,UFLB对胎儿PH的产前诊断具有一定意义。
Objective To observe the feasibility of virtual organ computer-aided analysis（VOCAL）technique in estimating the fetal lung volume,and to assess the diagnostic value of ultrasound fetal lung to body weight ratio（UFLB）in fetal pulmonary hypoplasia（PH）.Methods A total of 35 fetuses（16-36 weeks）with congenital malformation diagnosed with prenatal ultrasonography were enrolled in this study.The autopsy was permitted.The fetal lung volume was estimated with three-dimensional ultrasonography using VOCAL technique,while the fetal weight was measured with 2D ultrasonography with Hadlock equation.The lung volume obtained with VOCAL technique was compared with the actually measured volumes postnatally,and the value of UFLB in the diagnosis of fetal PH was evaluated.Results The bias of the fetal lung volume obtained with the two methods was（-0.81±1.77）cm3.The sensitivity,specificity,positive and negative predictive values of UFLB in diagnosing fetal PH was 83.33%,95.65%,90.91% and 91.67%,respectively,and the accuracy was 91.43%.Conclusion The fetal lung volume can be estimated precisely with three-dimensional ultrasonography using VOCAL technique.UFLB may be useful in the prenatal diagnosis of fetal PH.
出处
《中国介入影像与治疗学》
CSCD
2010年第4期413-416,共4页
Chinese Journal of Interventional Imaging and Therapy
基金
"十一.五"国家科技支撑计划项目(2006BA105A04)
关键词
超声检查
产前
肺发育不良
胎儿
Ultrasonography
prenatal
Pulmonary hypoplasia
Fetus
