摘要
目的探讨天然药物青蒿素及其衍生物的药理作用及机理。方法复习近年来国内、外相关文献并进行综述。结果青蒿素及其衍生物结构独特、高效低毒,除具有抗疟疾作用外,亦被证明具有抗肿瘤、调节免疫功能、抗菌、抗孕、抗纤维化、清热解毒等药理作用。结论青蒿素及其衍生物通过不同的途径发挥药理作用,具有较好的应用前景。
Objective To investigate the pharmacological effects and mechanisms of natural medicine artemisinin and its derivatives.Methods The pertinent domestic and overseas literatures of recent years were reviewed and summarized.Results Artemisinin and its derivatives have unique structure,high efficiency with low toxicity.The pharmacological effects include anti-malaria,anti-tumor,immune function regulation,anti-bacterial,anti-fetation,anti-fibrosis,heat-clearing and detoxicating,etc.Conclusion Artemisinin and its derivatives play pharmacological effects in different ways,and have a good foreground in the application.
出处
《中国普外基础与临床杂志》
CAS
2010年第5期519-521,共3页
Chinese Journal of Bases and Clinics In General Surgery
关键词
青蒿素
青蒿素类衍生物
药理作用
抗肿瘤
免疫机理
Artemisinin
Artemisinin derivatives
Pharmacological action
Anti-tumor
Immune mechanism
