摘要
目的探讨原发性高血压患者高敏C反应蛋白(high sensitivity C-reactive protein,hs-CRP)与腰臀比关系是否存在性别差异。方法选择原发性高血压患者111例,男63例,女48例,对不同性别高血压患者危险因素、血脂水平、hs-CRP、腰臀比进行比较。结果男性与女性高血压患者在年龄、体重指数、血压分级、糖尿病及冠心病发生率、早发冠心病家族史、TG、LDL-C、肌酐、hs-CRP等方面差异无统计学意义,而女性高血压患者TC、HDL-C、腰臀比明显高于男性高血压患者;女性高血压患者吸烟和饮酒率明显低于男性高血压患者,差异有统计学意义(P<0.05,P<0.01)。男性与女性高血压患者hs-CRP与腰臀比呈正相关(男:r=0.210,P<0.05;女:r=0.397,P<0.01),女性腰臀比相关系数高于男性。结论女性高血压患者更易出现中心型肥胖,腰臀比与hs-CRP关系更为密切。
Objective To study gender differences in relationship of high sensitivity C-reactive pro- tein（hs-CRP） with waist-hip ratio（WHR） in essential hypertensives. Methods Hypertension risk factors, blood lipids, hs-CRP, WHR, and the relationship of hs-CRP with WHR were analyzed in 111 essential hypertensives： 63 in male hypertensive group and 48 in female hypertensive group. Results There were no significant differences in age,body mass index, hypertension grade, TG, LDL-C,creatinine,hs-CRP,rates of diabetes and coronary heart disease between the two groups. Compared with male hypertensive group, TG, HDL-C and WHR of female hypertensive group were significantly higher; while, the rates of smoking and drinking were lower （P 〈 0.05,P 〈0.01）. Hs-CRP was positively correlated with WHR in both groups,but the relationship between hs-CRP and WHR was more significant in female hypertensive group（male： r = 0. 210, P 〈 0.05; female： r = 0. 397,P 〈 0. 01）. Conclusion Hypertensive woman is more susceptible to central obesity and significant correlation between hs-CRP and WHR.
出处
《中华老年心脑血管病杂志》
CAS
北大核心
2010年第5期400-402,共3页
Chinese Journal of Geriatric Heart,Brain and Vessel Diseases
基金
北京市自然科学基金(7072032)
关键词
高血压
C反应蛋白质
腰臀比
肥胖症
危险因素
hypertension
C-reactive protein
waist-hip ratio
obesity
risk factors
