摘要
目的探讨心肌梗塞患者高同型半胱氨酸(HCY)与凝血功能水平的关系。方法选择30例高HCY心肌梗塞住院患者为观察组,38例健康体检者为正常对照组,分别检测观察组及正常对照组HCY、国际凝血酶原比值(PT-INR)、活化部分凝血活酶时间(APTT)、纤维蛋白原(FIB)。结果观察组血清HCY、血浆FIB结果比正常对照组显著增高,差异有统计学意义(P<0.05);血浆PT-INR、APTT较正常对照组时间缩短,差异也有统计学意义(P<0.05)。结论心肌梗塞患者高同型半胱氨酸(HCY)与凝血功能水平的改变有密切的关系,同时检测同型半胱氨酸和凝血功能在心肌梗塞治疗和疗效观察中有着重要的临床意义。
Objective To investigate the relationship between high homocysteine（HCY） and the level of coagulation function in patients with myocardial infarction.Methods 30 cases of myocardial infarction inpatients with high HCY selected,38 cases of healthy peoples as control group,HCY,PT-INR,APTT and FIB were detected.Results The results of serum HCY and plasma FIB of observation group were markedly higher than those of the control group,there were significant differences（P0.05）;The results of plasma PT-INR,APTT were shortened when compared with the normal control group,there were significant differences too.Conclusion The myocardial infarction in patients with high homocysteine was closely related to the level of coagulation function changed.Simultaneous detection of HCY and coagulation function had an active clinical meaning to diagnose and observation of disease.
出处
《中华全科医学》
2010年第5期639-640,共2页
Chinese Journal of General Practice
关键词
心肌梗塞
高同型半胱氨酸
凝血功能
Myocardial infarction
Homocysteine
Coagulation function
