摘要
目的探讨血管性帕金森综合征(VP)与帕金森病(PD)的临床及影像学特征,为临床诊断提供帮助。方法对比分析22例VP及PD的病例资料。结果VP的发病年龄(64±4.7)岁,大于PD(54±5.6)岁,全部存在脑血管病的危险因素,多急性起病(12例,54.6%),发病时症状多较对称(15例,60%),四主征中震颤少见(3例,13.6%),与PD有明显不同;影像学上VP均可见脑梗死,以双侧基底节区脑梗死多见(20例,90.9%),PD组中特征性改变为T2WI上黑质致密带(SNc)变窄、边缘模糊,纹状体区信号减低。结论VP与PD在临床表现及影像学上均存在较大差异,综合分析结合影像特点有助于正确诊断。
Objective Analyzing the clinical and imaging features of vascular Parkinsonism （VP） and Parkinson disease （PD） to assist the diagnosis.Methods Contractively analyzing the data of 22 patients with VP and 22 patients with PD.Results The average paroxysmal age of 22 VP patients（64±4.7years） was more than that of 22 PD patients（54±5.6years）;The risk factors of cerebral vascular disease were found in all 22 VP cases;most VP cases had an acute onset（12cases,54.6%） and appeared symmetric symptoms（15cases,60%）;The tremor was only seen in 3 VP cases（13.6%）;The effective rate of L-dopa therapy to VP was relatively low（6 cases 27.3%）;To sum up,the clinical manifestations of VP cases were obviously different from those of PD cases;Imaging features：cerebral infarction lesions were found in all 22 VP cases and most lesions located in basal nucleus area（20 cases 90.9%）;T2WI examinations of PD cases represented narrowed,blurry-edge substantial nigra pars compacta and hypointense corpus striatum area.Conclusion Vascular Parkinsonism and Parkinson disease are remarkably different in clinical and imaging manifestations.Combining the two aspects to analyze,correct diagnosis is easier to achieve.
出处
《当代医学》
2010年第12期8-9,共2页
Contemporary Medicine
