摘要
戊型肝炎(Hepatitis E,HE)是由戊型肝炎病毒(Hepatitis E virus,HEV)引发的一种急性病毒性肝炎,其宿主广,可感染多种动物,但临床症状不明显。文章通过对其病毒形态学、分子生物学、感染宿主、流行状况、诊断、疫苗研制等研究进展进行概述,并结合广西HE的流行特点及其毒株基因型,提出今后应加强广西HE分子流行病学、病原学、病原生态学、疾病传播及感染致病的分子机制、快速特异诊断技术和防控技术等研究。
Hepatitis E (HE) is an acute transmitting non-A, non-B hepatitis which is caused by hepatitis E virus (HEV). The host of the HE virus is very extensive and can infect many animals without imperceptible clinical symptoms. The present study summarizes the research progress on the viral morphology, molecular biology, infected host, epidemic state, diagnosis and vaccine development for HE virus. According to the epidemic characteristics of HE and strain genotype of virus occurring in Guangxi, it would be of immense importance to prevent and effectively control the HE in animal as well as in human beings through a proper study of biological epidemiology, etiology, pathogen ecology, molecular mechanism of pathogenesis.
出处
《广西农业科学》
CAS
CSCD
2010年第2期179-182,共4页
Guangxi Agricultural Sciences
基金
广西基本科研业务费专项项目(桂兽研08-3)