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失血性休克患者D-二聚体、血栓调节蛋白水平的变化 被引量:2

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摘要 目的探讨失血性休克患者D-二聚体(D-D)、血栓调节蛋白(TM)水平的变化。方法选择43例失血性休克患者作为失血性休克组,另10例健康人为正常组。正常组采外周静脉血1次,失血性休克组分别于病后1、3、7d空腹采集外周静脉血,应用ELISA方法测定TM水平,全自动乳胶微粒增强免疫比浊分析方法测定血浆D-D水平。结果失血性休克组血浆D-D、TM水平伤后均明显高于正常组,失血性休克组在休克纠正后D-D水平逐渐降低,而TM水平迅速降低;血浆D-D和TM水平相互之间在各个时相点呈明显的正相关。结论休克后急性期D-D和TM水平的升高程度与休克严重程度有关,因此,测定失血性休克患者急性期外周血浆D-D和TM水平变化对预测休克的预后具有一定价值。
出处 《河北医药》 CAS 2010年第4期439-440,共2页 Hebei Medical Journal
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