摘要
目的探讨螺内酯对急性心肌梗死患者心功能综合指数（Tel指数）的影响。方法选择ST段抬高心肌梗死患者90例，采用随机数字表法分为螺内酯组和对照组各45例。对照组给予常规治疗，螺内酯组在对照组基础上口服螺内酯20mg／d，治疗6个月，治疗前后检测Tei指数并进行分析。结果治疗前2组患者的Tei指数比较，差异无统计学意义；治疗后螺内酯组的Tei指数为（0．53±0．16），明显低于对照组（0．62±0．14），差异有统计学意义（P〈0．05）。结论螺内酯可减低AMI后患者的Tel指数水平，具有改善心功能的作用。
Objectives To study the impact of spironolactone on Tei index in patients with acute myocardial infarction（AMI）. Methods Ninety cases of patients with ST-segment elevation myocardial infarction were selected and randomly divided into two groups. Forty-five cases in control group were given routine therapy and 45 cases in spironolactone group were given 20 mg spironolactone once a day on the basis of the same routine therapy as con- trois. The levels of Tel index were measured before and after the treatment of 6 months. Results There was no sig- nificant difference between two groups before treatment （ P 〉 0.05 ）. After treatment Tel index of spironolactone group（0.53 ± 0. 16） was significantly lower than control group （0. 62 ± 0. 14） （ P 〈 0. 05 ）. Conclusions Spironolactone can reduce the level of Tel index and improve the cardiac function of patients with AMI.
出处
《中国医药》
2010年第3期203-204,共2页
China Medicine
关键词
急性心肌梗死
螺内酯
TEI指数
Acute myocardial infarction
Spironolaetone
Tel index
