摘要
目的:探讨血清cTnI与非心源性危重症患者病情严重程度和预后的相关性。方法:将66例非心源性危重症患者根据入院后96h内cTnI是否有异常升高,分为高危组和低危组,分析两组患者急性生理和慢性健康状况评分Ⅱ(APACHEⅡ)分值、ICU住院时间、ICU住院费用、机械通气情况、30d病死情况的差异。结果:高危组的APACHEⅡ评分、ICU住院时间、ICU住院费用、机械通气人次、30d内病死人数均高于(多于)低危组(P<0.05或P<0.01)。结论:非心源性危重症患者血清cTnI的含量可在相当程度上反映患者病情的严重程度,并对患者的短期病死率预估有一定的帮助;因此cTnI可作为APACHEⅡ评分系统之外评价危重症患者病情与预后的重要指标。
Objective To investigate the relationship between serum cardiac troponin I（cTnI） levels and the severity and outcome in patients with noncardiogenic critical illness.Methods Serum cTnI levels were determined with CLIA in 66 non-cardiogenic critical patients immediately after admission and every 24h for 4 times.Those with serum cTnI levels always below 0.1ng/ml were designated as low risk（Group A,n=36） and the rest were designated as high risk（Group B,n=30）.The acute physiology and chronic health evaluationⅡ（APACHEⅡ） score,ICU hospitalization duration and expense,the number of patients received mechanical ventilation and 30-day mortality rate were examined in all the 66 patients.Results All the above parameters from the high-risk group were significantly higher than those of the low-risk group（P0.05 or P 0.01）.Conclusion The level of cTnI in patients with noncardiogenic critical illness could reflect the severity and might be taken to predict the shortterm mortality rate to some extent.Therefore,it is an important indicator in addition to APACHE Ⅱ scoring system for evaluation the sutcome of critical patients.
出处
《放射免疫学杂志》
CAS
2010年第1期68-69,共2页
Journal of Radioimmanology
基金
苍南县社会科技发展基金项目:项目编号:2007S11
