摘要
目的:比较国产头孢西丁、头孢呋辛、头孢他定在治疗社区获得性肺炎(CAP)的临床疗效、细菌清除率和安全性。方法:选择呼吸内科收住的120例社区获得性肺炎患者,随机分组,第一组(治疗组)40例采用头孢西丁治疗;第二组(对照组)40例采用头孢呋辛治疗;第三组(对照组)40例采用头孢他定治疗。观察疗效、细菌学检查并监测不良反应。结果:治疗组有效率77.3%;第二组有效率50.0%;第三组有效率63.6%。头孢西丁的细菌清除率较高。结论:头孢西丁治疗社区获得性肺炎的疗效、细菌敏感率优于常用头孢菌素,且安全性好。
OBJECTIVE To compare the therapeutic effect, bacterium clearance rate and safety of domestic cefoxitin sodium for injection for the treatment of community acquired pneumonia （CAP）. METHODS 120 patients of community acquired pneumonia （CAP） were selected from our courtyard breath internal medicine department by random allocation, the first group （treatment group） 40 patients given cefoxition to treat,the second group（control group） 40 patients given cefuroxime to treat, the third group（control group） 40 patients given ceftazidime to treat. The objective of all these three kind of medical treatment is to observe curative effect, inspect the bacteriology and monitor the adverse reaction. RESULTS Effectiveness of treatment group was 77. 3%,effectiveness of second group was 50. 0%, effectiveness of third group was 63.6% respectively. Percentage of bacterium clearance of cefoxitin was higher. CONCLUSION The effectiveness of cefoxitin and the bacteria of susteptibility is better and safer than that of common cephalosporins.
出处
《中国医院药学杂志》
CAS
CSCD
北大核心
2010年第2期151-153,共3页
Chinese Journal of Hospital Pharmacy
