摘要
目的研究经鼻持续气道正压（NCPAP）改善婴儿左向右分流先心病并心衰患儿心肺功能的效果，评价该治疗方法的优点和安全性。方法左向右分流先心病并心衰患儿40例，20例随机分配到NCPAP组，予NCPAP治疗。其余20例作为对照组，给予面罩供氧治疗，综合治疗两组相同。在开始治疗时和治疗后1、12、24h记录呼吸频率、心率、PaO2、PaCO2、pH值、PaO2／FiO2等。结果治疗后1hNCPAP组呼吸频率、心率明显改善（P〈0．05）；PaO2和PaO2／FiO2均较对照组明显上升（P〈0．05），PaCO2较对照组下降（P〈0．05），且此趋势随时间推移持续。NCPAP组气管插管率显著低于对照组（P〈0．05）。结论NCPAP可改善左向右分流先心病并心衰患儿心肺功能和临床症状、体征，降低患儿气管插管的风险。
Objective To investigate the effectiveness of nasal continuous positive airway pressure （NCPAP） in improving cardiorespiratory function in left-to-right shunt congenital heart disease infants with heart failure. Assess method quality and safety. Methods Forty left-to-right shunt congenital heart disease infants with heart failure were divided into 2 groups, a group that included 20 patients who decided to receive NCPAP and a control group of 20 patients that received face mask ventilation. Both groups were given conventional medications. Vital signs, PaO2 , PaCO2 ,pH, and PaO2/FiO2 were recorded at the start and 1,12, and 24 hrs into the study. Results Heart rate and respiratory rate with NCPAP improved significantly （ P 〈 0. 05 ）. PaO2 and PaO2/ FiO2 improved significantly compared with control group after 1 hrs. （ P 〈 0.05, respectively）. The trend continued over time. The endotracheal intubation was significantly lower in the NCPAP group than in the control group （ P 〈 0. 05 ）. Conclusion Treatment with NCPAP improves cardiorespiratory function and the signs and symp- toms of left-to-right shunt congenital heart disease infants with heart failure. NCPAP seems to afford these patients protection from endotracheal intubation.
出处
《中国临床实用医学》
2010年第2期21-22,共2页
China Clinical Practical Medicine
关键词
经鼻持续气道正压
先天性心脏病
心力衰竭
婴儿
Nasal continuous positive airway pressure
Ccongenital heart disease
Heart failure
Infants
