摘要
目的探讨胃肠间质瘤(gastrointestinal stromal tumor,GIST)CT诊断价值。方法回顾性分析39例经手术病理和免疫组织化学证实的GIST患者的临床及CT检查资料,并将CT表现与病理诊断进行对照。结果39例GIST中,良性共9例,恶性共30例。发生在胃肠道26例恶性19例,发生在胃肠道外13例恶性11例;肿瘤<5cm组14例恶性7例,肿瘤≥5cm组25例恶性23例;有囊变坏死30例恶性29例,无囊变坏死9例恶性1例;11例有转移均为恶性,28例无转移恶性19例。GIST的发病部位、大小、有无囊变坏死及转移对肿瘤的良恶性的鉴别有统计学差异(P<0.05)。发生在胃肠道外的GIST恶性程度高,肿瘤≥5cm组恶性程度较高,且肿瘤的大小与肿瘤恶性程度呈显著正相关,有囊变坏死及转移的GIST恶性程度高。结论CT检查对GIST的定位、定性诊断有重要价值,多种CT征象有助于对GIST良、恶性做出准确判断。
Objective To investigate the malignant degree diagnostic value of CT in gastrointesfinal strornal tumor（GIST）. Methods CT data of 39 cases with GIST confirmed by pathology and immtmohistochemistry were retrospectively analyzed. The CT features of GIST were COlnpared with the pathologic findings. Results In 39 cases of GIST, the total benign tumors were 9 cases, malignant tumors were 30 cases. Tumors situated at gastrointestinal tract were 26 cases with mafignant tumor 19 cases, extra-gaslrointestinal tract 13 cases with malignant tumor 11 cases, size less than 5cm 14 cases with malignant minor 7 cases, large than or equal to 5cm 25 cases with malignant tumor 23 cases, necrosis 30 cases with malignant 29 cases, no necrosis 9 cases with malignant 1 case. 11 cases of metastatic tumors were all malignant. In 28 cases of no metastatic tumors 19 cases were malignant. The site, size, metastasis and necrosis of GIST had the significant difference statistical significance in identifying benign or malignant tumors 0P 〈0.05）. Malignant GIST was more frequently observed in extra-gastrointestinal tract. GIST large than 5 centimeters was more malignant. The size and malignancy degree were a significant positive correlation, GIST with metastasis and necrosis was liable more malignant. Conclusion CT examination is helpful for GIST location and differential diagnosis. Multiple kinds of CT features are helpful for exactly judging the grade of GIST by pathology.
出处
《中国CT和MRI杂志》
2010年第1期55-57,共3页
Chinese Journal of CT and MRI
关键词
胃肠道间质瘤
体层摄影术
X线计算机
gastrointestinal stromal tumor
tomography, X-ray computer
