摘要
目的：探讨激素和生长因子对人牙乳头细胞骨钙素合成分泌的影响；方法：采用放射免疫的方法进行测定。结果：１，２５（ＯＨ）２Ｄ３对骨钙素的合成分泌具有明显增强作用，胰岛素、ＥＧＦ对其合成有促进作用，但较弱。而ＴＧＦ－β抑制骨钙素的合成分泌。结论：人牙乳头细胞合成分泌骨钙素受这些因子不同程度的影响。
Aim: To study the effects of 1,25(OH) 2D 3, Insulin , EGF and TGF-β on the osteocalcin secretion of human dental papilla cells in vitro. Methods:A radioimmunological method was used to determine the osteocalcin secrection by the human papilla cells. Results: 1,25(OH) 2D 3 could stimulate osteocalcin secretion dramatically, but TGF-β inhibited its secretion. Conclusions: These results suggested that these factors may act as regulators of osteocalcin secretion of human dental papilla cells in vitro.
出处
《牙体牙髓牙周病学杂志》
CAS
1998年第4期258-259,共2页
Chinese Journal of Conservative Dentistry
关键词
人牙乳头细胞
骨钙素
细胞培养
放射免疫
human dental papilla cell osteocalcin cell culture radioimmunology 1,25(OH) 2D 3 EGF Insuline TGF-β
