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DNA甲基化与恶性血液病的研究进展

Progress of DNA methylation in malignant hematological disease
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摘要 甲基化修饰是DNA的一种正常自然修饰方式，在基因表达的调控、基因结构的稳定等方面有不可或缺的地位。抑癌基因的高甲基化失表达在恶性血液病的发生发展过程中起着重要作用。甲基化研究可用于恶性血液病的诊断、抑癌基因的筛选、微小残留病灶的检测及疗效、预后判断，去甲基化治疗已成为恶性血液病治疗的又一重要途径。
作者 曹岚(综述) 柴忆欢(审校)
机构地区 苏州大学附属儿童医院
出处 《国际儿科学杂志》 2009年第6期573-576,共4页 International Journal of Pediatrics
关键词 DNA甲基化 恶性血液病
分类号 R730.231 [医药卫生—肿瘤] R733 [医药卫生—肿瘤]
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参考文献30

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国际儿科学杂志
2009年 第6期

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