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舒芬太尼延迟性预处理对大鼠心肌缺血再灌注损伤早期细胞凋亡的影响 被引量：3

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摘要 心肌缺血再灌注损伤（myocardial ischemic reperfusion injure，MIRI）是影响患者康复和手术成功的重要因素。心肌缺血预处理可使心脏对随后更严重的缺血损伤产生较强的耐受能力。近年来药物预处理尤其是延迟性预处理成为防治MIRI的研究热点。舒芬太尼（sufentainil）是一种新合成的强效拟吗啡类镇痛药，尤其适于心血管麻醉。本研究拟评价舒芬太尼延迟性预处理对大鼠心肌缺血再灌注损伤的影响及作用机制，为围手术期用药提供参考。
作者 杨玲 黄彤
机构地区 山西医科大学第一医院麻醉科 山西医科大学第一医院感染科
出处 《中国药物与临床》 CAS 2009年第11期1073-1074,共2页 Chinese Remedies & Clinics
关键词 心肌缺血再灌注损伤 延迟性预处理 舒芬太尼 细胞凋亡 损伤早期 大鼠 围手术期用药 心肌缺血预处理
分类号 R96 [医药卫生—药理学]
  • 相关文献

参考文献13

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共引文献8

同被引文献20

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引证文献3

二级引证文献19

中国药物与临床
2009年 第11期

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