摘要
目的应用血清流行病学调查广州市禽类从业人群感染禽流感病毒H5N1、H9N2、H7N7的状况，分析其感染特征。方法采集广州市与禽类接触相关的职业人群血清，包括农贸市场活禽零售与非禽类零售人群、企业化家禽养殖与农村家禽散养人群、活禽批发市场人群、野生鸟驯养人群、生猪屠宰人群以及一般人群，用血凝抑制试验、中和抗体试验检测H5、H9、H7IgG抗体；使用logistic回归分析、χ^2检验分析感染率分布。结果2881名调查对象中检测出4例H5抗体阳性（0．14％）；146例H9抗体阳性（5．07％），其中以活禽零售人群H9感染率最高（14．96％），企业化家禽养殖人群为8．90％，活禽批发人群为6．69％，野生鸟驯养人群为3．75％，生猪养殖人群为2．40％，非禽类零售人群为2．21％，农村家禽散养人群为1．77％，一般人群为2．30％。而1926名禽类从业人群中H7抗体均为阴性。结论人群中H5感染率较低，而H9感染率较高，未检测到H7感染；活禽零售、家禽批发、企业化家禽养殖等职业具有较高感染禽流感病毒的风险，其中以活禽零售感染风险最高，且接触家禽时间越长感染风险越高。
Objective To conduct ser logi 1 investig ion on H5N1/H9N2/H7N7 infection among people occupied in poultry fields. Methods Serum samples were collected from people working in live poultry and none-poultry retailing food markets, poultry wholesaling, large-scale poultry breading factories and in small-scale farms, wide birds breeding, swine slaughtering houses and from normal population. Antibodies of H5, H9 and H7 with hemagglutination inhibition and neutralization tests were tested and analyzed. Logistic regression and χ^2 test were used. Results Among 2881 samples, 4 were positive to H5-Ab（0.14%）, 146 were positive to H9-Ab （5.07%） and the prevalence of H9 among people from live poultry retailing （14.96%） was the highest. Prevalence rates of H9 were as follows： 8.90% in people working in the large-scale poultry breading factories, 6.69% in the live poultry wholesaling business, 3.75% in the wide birds breeding, 2.40% in the swine slaughtering, 2.21% in the non-poultry retailing, 1.77% in the rural poultry farmers and 2.30% in normal population. None was positive to H7-Ab among 1926 poultry workers. Conclusion The H5 prevalence among people was much lower than expected, but the H9 prevalence was higher. None of the populations tested was found positive to H7-Ab. There was a higher risk of AIV infection in live poultry retailing, wholesaling and large-scale breading businesses, with the risk of live poultry retailing the highest. The longer the service length was, the higher the risk existed.
出处
《中华流行病学杂志》
CAS
CSCD
北大核心
2009年第11期1111-1113,共3页
Chinese Journal of Epidemiology
基金
广州市科技局项目（2005J3-E0611/2006Z3-E5141）
