摘要
目的采用双心腔起搏治疗肥厚性梗阻型心肌病１１例，并观察其血液动力学效果。方法１１例患者，男８例，女３例，平均年龄４１岁，均确诊为肥厚性梗阻型心肌病；所有患者均有头晕、活动后气短等临床症状，其中６例患者有晕厥史；超声心动图检查，平均室间隔厚度为２．２ｃｍ，左室流出道压力差平均为４９．０５ｍｍＨｇ（１ｍｍＨｇ＝０．１３３ｋＰａ）。所有患者均置入双心腔起搏器治疗并观察其血液动力学改变。结果在以较短的房室间期（１００ｍｓ）进行双心腔起搏器起搏后，左室流出道压力差从４９．０５ｍｍＨｇ下降至１９．０７ｍｍＨｇ，Ｐ＜０．０５；患者临床症状明显改善，在平均随访９个月中（５～１６个月），无１例患者发生晕厥。结论双心腔起搏治疗肥厚性梗阻型心肌病是一种有效的新的治疗方法，临床应用时应注意选择合适的起搏参数。
Objective We report our clinical use of duel chamber pacing in patients with hypertrophic obstructive cardiomyopathy (HOCM) and its hemodynamic effects. Methods Eleven Patients (8 male and 3 female, mean age of 41 years) with HOCM were implanted permanent duel chamber pacemaker. All patients had clinical symptoms refractory to medical therapy (β blockers and/or Ca 2+ blockers) and 6 of them had syncope. The mean thickeness of ventricular septum was 2.2cm.Results The symptoms were significantly improved in 9 patients after pacing with short A V delay. The left ventricular outflow tract (LVOT) pressure gradients were reduced from 49.05 mmHg to 19.07 mmHg after pacing ( P <0.05). In the follow up of 9 months (5 16 months), no patients had syncope.Conclusion Duel chamber pacing is an effective new method to treat patients with HOCM.
出处
《中华心血管病杂志》
CSCD
北大核心
1998年第5期362-363,共2页
Chinese Journal of Cardiology
关键词
心肌病
肥大性心肌病
心脏起搏
血液动力学
cardiomyopathy
hypertrophic
cardiac pacing
artificial
hemodynamics
