摘要
目的测量并评价活动性肺结核患者的生存质量（ＱｏＬ）。方法采用ＳＦ３６、生存质量指数、ＫＰＳ等量表，对２２８例活动性肺结核患者和２２８例正常对照进行ＱｏＬ测量与评价，并对ＱｏＬ的影响因素进行单因素分析和多因素逐步回归分析。结果肺结核患者的平均ＳＦ３６总评分及生理机能、角色生理状况、心理健康状况、角色心理状况、社会机能、活力、躯体疼痛和主观健康状况的平均评分分别为５７±１７、６５±２８、２２±３２、６１±２０、３０±３６、５４±２７、５６±２１、６５±２４和５３±１５，与对照组（分别为７７±８、８４±２３、８１±３４、７５±１８、８１±３３、８３±２３、６１±２１、７５±２４和７２±２０）相比，差异有非常显著性（Ｐ均＜０．０１）；肺结核患者的平均生存质量指数评分（７．４±２．０）和平均ＫＰＳ评分（７７±１７）与对照组（分别为９６±０８和９７±９）相比，差异亦有非常显著性（Ｐ均＜０．０１）。肺结核患者ＳＦ３６总评分及其８个分项目相互之间的相关系数均具有显著性意义（Ｐ均＜０．０１），ＳＦ３６总评分与生存质量指数评分呈极显著性正相关（ｒ＝０．７８４１，Ｐ＜０．００１）、与ＫＰＳ评分呈极显著性正相关（ｒ＝０?
Objective To measure and assess the quality of life (QoL) of patients with pulmonary tuberculosis. Method QoL of 228 patients with pulmonary tuberculosis and 228 healthy controls were marked by MOS SF 36, QLI and KPS scales, and single and multiple stepwise regression analysis were made to evaluate factors affecting QoL. Result The average total mark of SF 36, marks of physical functioning, role physical, mental health, role emotional, social functioning, vitality, bodily pain and general health were respectively 57±17, 65±28, 22±32, 61±20, 30±36, 54±27, 56±21, 65±24 and 53±15 in the pulmonary tuberculosis group, while 77±8, 84±23, 81±34, 75±18, 81±33, 83±23, 61±21, 75±24 and 72±20 in the controls. Statistically significant differecnes were found between the two groups (all P values <0.01). The average marks of QLI and KPS were 7.4±2.0 and 77±17 respectively in the pulmonary tuberculosis group, and significant differences were also found comparing with the controls (9.6±0.8, 97±9) ( P <0.01). There were statistically significant correlation among the total mark of SF 36 and the marks of the above 8 subdivisions in patients with pulmonary tuberculosis. The correlation coefficients between marks of SF 36 and QLI, KPS were 0.7841, 0.8931 respectively ( P <0.001). The factors affecting the marks of SF 36 of the patients were focus size of infection, counts of white blood cells, complications, elevated ALT and duration of disease. Conclusion The SF 36 scale is suitable for measurement of QoL of patients with pulmonary tuberculosis. The QoL of patients with pulmonary tuberculosis declines. The main factors affecting the QoL of the patients are focus size of infection, counts of white blood cells, complications, elevated ALT and duration of disease.
出处
《中华结核和呼吸杂志》
CAS
CSCD
北大核心
1998年第12期720-723,共4页
Chinese Journal of Tuberculosis and Respiratory Diseases
关键词
肺结核
生存质量
测量
评价
Tuberculosis, pulmonary Quality of life
