摘要
由于炎症、外伤、肿瘤、功能性萎缩及其他切除性手术等原因引起的颁骨缺损严重影响患者的面容和口腔功能,也给患者后续的义齿修复工作带来很大的困难。颌骨重建技术的最终目标是获得具有生理功能的颌骨,容纳种植体、利于义齿修复等,以恢复面部形态及咬合功能。近年来研究表明,富血小板血浆(platelet-richplasma,PRP)因含有多种高浓度的生长因子,可加快成骨速度、提高成骨质量。我们对PRP及其在颌骨修复重建中的作用作一综述。
出处
《现代实用医学》
2009年第8期912-914,共3页
Modern Practical Medicine
参考文献24
-
1Marx RE, Carlson ER, Eichstaedt RM, et al,Platelet-rich olasma:growthfactor enhancement for bone grafts[J].Oral Surg. 1998,85(6):638-646.
-
2Okuda K, Kawase T,Momose M, et al. Platelet-rich plasma contains high levels of platelet-derived growth factor and transforming growth factor-beta and modulates the proliferation of periodongtaUy related cells invitro[J]. J Periodontol,2005,74(6):849-857.
-
3Gerard D,Garlson ER,Gotcher JE,et al. Effects of platelet-richplasma on the healing autologous bone grafted mandibular defects in dogs [J].J Oral Maxillofac Surg, 2006,64(3):443-451.
-
4蔡华雄,宋洁文,赵小朋,阮毅,郑美华,李海刚.富含血小板血浆和rhBMP-2复合物诱导兔下颌骨再生的实验[J].中山大学学报(医学科学版),2007,28(4):430-433. 被引量:5
-
5Fennis JPM, Stoelinga PJW, Jansen JA. Mandibular reconstruction: a histologicaland histomorphometric studyon the use of autogenous scaffolds, particulate cortico- cancellous bone graftsand platelet rich plasma in goats[J]. Int J Oral Maxillofac Surg, 2006,33(1):48-55.
-
6Kovacs K, LinksSuba Z,Takacs D.Facilitation of beta-tricalcium phosphate-inducedalveolar bone regeneration by platelet-- rich plasma in beagle dogs: a histologic and histomorphometric study[J].Int J Oral Maxillofac Implants,2004, 19(6): 832-838.
-
7施斌,周毅,王贻宁,程祥荣.种植前牙槽骨保存的动物实验[J].中华口腔医学杂志,2006,41(2):114-115. 被引量:3
-
8Bellie,Longo B,Balestra F M.Autogenous platelet-rich plasma in combination with bovine-derived hydroxyapatite xenografl for treatment of acystic lesionof the jaw [J].J Craniofac Surg,2005,16(6):978-980.
-
9Thor A. Reconstruction of the anterior maxilla with platelet gel, autogenous bone, and titanium mesh: a case report[J].Clin Implant Dent Relat Res,2005,4(3): 150-5.
-
10Sammartino G, Tia M, Marenzi G, et al. Use of autologous Platele-rich plasma (PRP) in perildontal defect treatment after extraction of impactedmandibular thirdrnolars[J]. Joral Maxillofac Surg,2005,63 (6):766-770.
二级参考文献39
-
1冉炜,郭冰,李轶,王迎军,葛建华.可降解骨组织工程支架材料修复兔下颌骨缺损的实验研究[J].中山大学学报(医学科学版),2004,25(B06):18-20. 被引量:4
-
2陈江,杨进,闫福华,赵欣.非诱导条件下犬骨髓基质细胞的生物学特性[J].福建医科大学学报,2004,38(4):361-364. 被引量:9
-
3邹培,李峻辉,李主一,周中英,林月秋,阮默.骨延长区组织愈合过程中胶原变化的偏光显微镜观察[J].中国修复重建外科杂志,2006,20(1):1-4. 被引量:2
-
4冯扬,唐休发.富血小板血浆在颌面部非血管化骨移植中的应用[J].中国修复重建外科杂志,2006,20(9):944-946. 被引量:7
-
5Kim SG, Kim WK, Park JC, et al. A comparative study of osseointegration of Avana implants in a demineralized freezed-driedbone alone or with platelet-rich plasma. J Oral Maxillofac Surg,2002, 60:1018-1025.
-
6Zecher W, Tang LS,Tepper G,et al. Lnfuence of platelet-rich plasma osseous healing of dental implants : a histologic and histomorphometric study in minipigs. Int J Oral Maxillofac Implant,2003,18:15-22.
-
7Chen ST, Wilson riG Jr, Hammerle CH. Immediate or early placement of implants following tooth extraction: review of biologic basis, clinical procedures, and outcomes. Int J Oral Maxillofac Implants,2004, 19 : 12-25.
-
8Intini G, Andreana S, Margarone JE 3rd, et al. Engineering a bioactive matrix by modifications of calcium sulfate. Tissue Eng,2002,8:997-1008.
-
9Cornelini R,Scarano A,Covani U,et al.Immediate one-stage postextraction implant:a human clinical and histologic case report.Int J Oral Maxillofac Implants,2000,15 (3):432-437.
-
10Ulm C,Solar P,Blahout R,et al.Reduction of the compact and cancellous bone substances of the edentulous mandible caused by resorption.Oral Surg Oral Med Oral Pathol,1992,74 (2):131-136.
共引文献15
-
1李雁,马国武.PRP在口腔种植中的研究进展[J].中国口腔种植学杂志,2008,13(1):40-43. 被引量:1
-
2仲维剑,马国武,张晓燕.骨引导再生技术在牙种植中的应用(英文)[J].中国组织工程研究与临床康复,2009,13(2):396-400. 被引量:2
-
3周立伟,魏世成,李玉宝,姜肖梅.纳米羟基磷灰石/聚酰胺66复合人工骨修复颅骨缺损的动物实验研究[J].口腔医学,2009,29(11):561-563. 被引量:16
-
4王华,邓春富,赵宝红,王飞.胶原膜的应用及固定对人工骨粉成骨效果的影响[J].口腔颌面外科杂志,2010,20(1):20-23. 被引量:8
-
5姚姝博,韩泽民,冯建华.牙槽骨骨量不足的病因及治疗方法探讨[J].广东医学,2011,32(23):3150-3152. 被引量:5
-
6丁建勇,魏琳,郭家平.不同类型骨移植材料修复牙周牙槽骨缺损[J].中国组织工程研究,2012,16(16):3033-3036. 被引量:9
-
7李守宏,尚政军.保持拔牙术后牙槽窝骨量的研究进展[J].现代口腔医学杂志,2012,26(3):195-200. 被引量:1
-
8胡钟旭,李东卿,李贵涛,杜恒胜.富血小板血浆联合骨髓间充质干细胞治疗家兔股骨头缺血坏死的研究[J].中华损伤与修复杂志(电子版),2014,9(1):22-26. 被引量:16
-
9谭鸾君,王磊.牙槽嵴保存的研究进展[J].中国口腔种植学杂志,2014,19(3):140-142. 被引量:1
-
10李思敏,周晋,颜承伟,宋鹏,郭良微.富血小板血浆缓释载体在骨组织工程中的研究进展[J].口腔医学研究,2015,31(6):632-634. 被引量:10
同被引文献19
-
1廖贵清,苏宇雄.牙源性肿瘤术后颌骨缺损的修复重建[J].中国实用口腔科杂志,2009,2(2):79-81. 被引量:6
-
2刘彦普,龚振宇,何黎升,赵晋龙,于擘,张海霞.大块下颌骨缺损的个体化数字设计及外形与功能重建[J].中国修复重建外科杂志,2005,19(10):803-806. 被引量:21
-
3韩建生,刘瑞敏,贾周太.聚乳酸、自体血、rhBMP-2复合体在颌骨缺损修复中作用的实验研究[J].口腔医学研究,2007,23(5):512-515. 被引量:5
-
4Wolfgang Schlickewei, Carsten Schlickewei. The Use of Bone Substit- utes in the Treatment of Bone Defects-the Clinical View and History [J]. Macromol.Symp, 2007, 253(1): 10-23.
-
5Massimo Robiony, MD, Iolanda Salvo, MD, Fabio Costa, MD, et al.Virtual reality surgical planning for maxillofacial distraction osteogen- esis:The role of reverse engineering rapid prototyping and cooperative work [J]. American Association of Oral and Maxillofacial Surgeons, 2007, 65(6): 1198-1208.
-
6Y. J. Hu, A. Hardiantol, S.Y.Li, et al. Reconstruction ofa palato- max- illary defect with vascularized iliac bone combined with a superficial inferior epigastric artery flap and zygomatic implants as anchorage[J]. Int J Oral Maxillofac. Surg, 2007, 36(9): 854-857.
-
7Jun-Young PAENG, Jee-Ho LEE, Jong-Ho LEE, et al. Condyle as the point of rotation for 3-D planning of distraction osteogenesis for he- mifacial microsomia[J]. J Cranio-Maxillofacial Surgery, 2007, 35(2): 91-102.
-
8D Eggbeer, PL Evans, R Bibb. A pilot study in the application of tex- ture relief for digitally designed facial prostheses[J]. J Engineering in Medicine, 2006, 5(220): 705-713.
-
9Carsten Westendorff, M.D., Jan Kaminsky, M.D., Ulrike Ememann, M.D., et al. Image-guided sphenoidwing meningioma resection and simultaneous computer-assisted cranio-orbital reconstruction: techni- cal case report[J]. J Operative neurosurgery, 2007, 2(60): 173-174.
-
10王思明,南欣荣.富血小板血浆复合自体松质骨微粒修复兔下颌骨缺损的实验研究[J].北京口腔医学,2008,16(4):191-194. 被引量:2
二级引证文献3
-
1陈建宇,罗崇岱,张春雨,张弓,邱伟前,张志光.计算机辅助设计及激光快速成形的纯钛髁突对重建颞下颌关节可行性探讨[J].中华口腔医学杂志,2014,49(10):625-630. 被引量:6
-
2林泽,陈军,李雪.数字化3D打印技术在口腔舌侧正畸托槽粘接中应用研究[J].中国实用口腔科杂志,2016,9(2):104-107. 被引量:19
-
3苏忠平,于擘.数字化3D打印技术在OSAHS治疗中的应用[J].中国实用口腔科杂志,2017,10(2):73-75.
-
1刘志辉,刘春丽,杨春英,王博蔚,秦绪喜.两种牵张方向对下颌骨体部牵张成骨影响的实验研究[J].实用口腔医学杂志,2009,25(1):18-21. 被引量:1
-
2郭志义,胡阳,庞明辉,李平.高龄胃癌病人的围手术期处理及营养支持[J].中国实用外科杂志,2005,25(3):154-156. 被引量:43
-
3杨静,王瑜,曹阳.个性化护理在口腔颌面部损伤病人中的应用[J].全科护理,2015,13(35):3553-3555. 被引量:6
-
4刁晓悦,柳忠豪.牙周组织再生治疗方法研究进展[J].中国口腔种植学杂志,2014,19(1):34-37. 被引量:3
-
5魏怡.牙菌斑、牙石、口臭及牙周病[J].健康必读,2002(12):53-53.
-
6王雯.羟基磷灰石在颌骨修复与修整中的应用[J].中国社区医师(医学专业),2007,9(24):110-110.
-
7蒋佩珏,叶明.带血管蒂游离髂骨移植修复下颌骨缺损及ECT骨显象的应用[J].中华肿瘤杂志,1989,11(3):199-200.
-
8谢占宏.高龄胃癌病人围手术期处理分析[J].医学理论与实践,2005,18(10):1162-1163. 被引量:2
-
9陈珊珊,马月华,范桂红.个性化冲洗法在口腔颌面外科口腔护理中的应用[J].中国继续医学教育,2016,8(14):217-218. 被引量:9
-
10文摘[J].口腔生物医学,2010,1(4):219-222.