摘要
目的分析2型糖尿病对骨质疏松发病率的影响及骨质疏松与年龄、体重指数、糖尿病的相关性。方法①选择102例2型糖尿病患者及146例对照组病例，测量其骨密度（BMD）值，采用病例对照法分析2型糖尿病对骨质疏松发病率的影响；②运用Logistic多元回归的方法分析糖尿病、年龄、性别、体重指数对骨质疏松的影响；③对糖尿病、年龄、体重指数与骨质疏松的相关性进行分析。结果①2型糖尿病组的骨质疏松发病率为55．9％，对照组为43．2％，糖尿病组高于对照组；②骨质疏松与年龄及糖尿病正相关，与体重指数负相关；糖尿病、性别、年龄及体重指数对骨质疏松的影响均有统计学意义；③糖尿病组的年龄、体重指数与骨质疏松的相关性均有统计学意义；④对照组的年龄对骨质疏松的相关性影响有统计学意义；⑤ward’s三角区为两组病例骨质疏松共同的好发部位。结论①2型糖尿病是骨质疏松的重要影响因素，与骨质疏松正相关；②2型糖尿病患者应保持适当的体重指数，以延缓骨质疏松的发生、减轻骨质疏松的程度；③无论有无糖尿病，中老年人均应定期检查BMD，以早期发现、早期治疗骨质疏松，降低由骨质疏松导致的腰椎、股骨骨折发生率，提高老年人生活质量。④ward’s三角区对骨质疏松最敏感，可作为首选检查部位。
Objective To investigate the effect of type 2 diabetes mellitus on incidence of osteoporosis and the correlation of osteoporosis with age, body mass index （BMI） and diabetes. Methods （1）The patients with type 2 diabetes mel]itus of 102 cases and control patients of 148 cases were selected to measure the Bone Mineral Density （BMD）, and the case-control study was used to analyze the effect of type 2 diabetes mellitus on incidence of osteoporosis ; （2）The logistic muhiple regression was used to analyze the influence of diabetes, age, sex and BMI on osteoporosis;（3）The correlation analysis of diabetes, age, BMI and osteoporosis was performed. Results （1）The group of type 2 diabetes mellitus had a higher osteoporosis incidence than the control group, ie. 55.9% and 43.2%, respectively; （2）The positive correlation of osteoporosis with age and diabetes was found out, with its negative correlation with BMI; the effect of diabetes, age, sex and BMI on osteoporosis had a statistical significance; （3）In the group of diabetes, the correlation of age and BMI with osteoporosis had a statistical significance; （4） In the control group, only age had a statistieal osteoporosis relevance; （5）The Ward＇s Triangle Area was the predilection site of osteoporosis. Conclusion （1）The type 2 diabetes mellitus is an important risk factor; （2）The patients with type 2 diabetes mellitus should maintain a proper BMI; （3） The regular examination of BMD should be performed for the middle-aged and elderly people in order to treat osteoporosis and prevent its complications; （4）The ward＇s triangle area was regarded as the first choice of examination for early diagnosis of osteoporosis.
出处
《中国骨质疏松杂志》
CAS
CSCD
2009年第8期568-571,586,共5页
Chinese Journal of Osteoporosis
关键词
2型糖尿病
骨质疏松
骨密度(BMD)
Type 2 diabetes mellitus
Osteoporosis
Bone mineral density （BMD）
