摘要
目的分析危重症新生儿肠外营养相关性胆汁淤积(PNAC)的危险因素。方法对接受肠外营养(PN)支持超过14d的116例新生儿的临床资料进行回顾性分析,分析其发生PNAC的危险因素。结果116例中发生PNAC31例(26.7%),分析结果显示胎龄、出生体质量、PN持续时间和感染与PNAC等有密切相关。其中PN持续时间是PNAC的独立高危因素。结论PN持续时间越长,发生PNAC的危险性越大,尽早肠内喂养,缩短PN时间,是降低PNAC的重要措施。
Objective To analyze the risk factors of parenteral nutrition-associated cholestasis （PNAC） in high-risk neonates. Methods A total of 116 cases who had accepted parenteral nutrition during the neonatal period for at least 14 days were included in this study. The risk factors of PNAC were analyzed. Results The incidence of PNAC was 26. 7%. Gestational age, birth weight, persistence time in PN and in- fection were all closely correlated with PNAC. The pesistance time in PN was an independent risk factor of PNAC. Conclusion The longer the persistence time, the more risk of happening of PNAC. Early enteral feeding and shortening the time of PN are the important measures to lower the incidence of PNCA.
出处
《中国中西医结合儿科学》
2009年第4期307-309,共3页
Chinese Pediatrics of Integrated Traditional and Western Medicine
关键词
婴儿
新生
疾病
肠外营养
胆汁淤积
肺炎
新生儿肺透明膜病
Infant,newborn/disease
Parenteral nutrition
Cholestasis
Pneumonia
Hyalinemembrane disease in neonates
