摘要
目的:回顾性分析卡前列素氨丁三醇在剖宫产术中使用时机,评价其使用价值。方法:在该产科剖宫产使用卡前列素氨丁三醇治疗156例病人,部分预防性使用,部分经徒手按摩子宫,追加催产素20～40U注射后子宫收缩仍然不良时,宫体注射卡前列素氨丁三醇。重复使用时,间隔时间大于15min。结果:卡前列素氨丁三醇注射后子宫变硬,出血减少,86%的病人在接受注射1针(250μg)情况下有效,96%的病人在用量为250μg或500μg时有效。不良反应颜面潮红、恶心、呕吐,症状轻微。结论:卡前列素氨丁三醇治疗剖宫产术中出血,适时使用,疗效迅速且不良反应少,且药费比输等量血费用更低,同时减少失血对患者身体的损害及输血风险,可作为产科急救用药或预防性用药。
Objective： To explore the applied opportunity and economical efficiency of carboprost tromethamine in cesarean section. Methods： 156 cases were treated by carboprost tromethamine in cesarean section, some of them used carboprost tromethamine for prophylactic treatment before operation, and the others used carboprost tromethamine after operation under different opportunities. All the cases were treated by 20 - 40 U oxytocin at the same time. Some cases needed more than 250μg carboprost tromethamine and 15 minutes interval between each injection was necessary. Results： The uterus became more harder and the hemorrhage volume became fewer after the injection of carboprost tromethamine, 250μg was effective dose for 86% of the cases and 250 μg or 500 μg were effective dose for 96% of the cases. The adverse reaction included facial blushing, nausea and vomitting. Conclusion： Carboprost tromethamine can prevent and decrease the hemorrhage volume and the risk of blood transfusion under postpartum hemorrhage.
出处
《中国妇幼保健》
CAS
北大核心
2009年第21期2925-2927,共3页
Maternal and Child Health Care of China
关键词
卡前列素氨丁三醇
使用时机
药物经济性
Carboprost tromethamine
Applied opportunity
Drug economical efficiency
