摘要
异化Fe(Ⅲ)还原菌不是分类学上的概念,它具有系统发育及环境来源多样性的特点。与其他大多数的电子受体不同,在近中性pH值条件下,Fe(Ⅲ)的溶解度很低,通常以不溶性的Fe(Ⅲ)氧化物的形式存在。目前,对微生物如何获得和还原不溶性Fe(Ⅲ)的机理仍缺乏系统的了解。以希瓦氏菌和地杆菌为例,本文综述了3种异化Fe(Ⅲ)还原的酶促反应机制及其分子调控机理:异化Fe(Ⅲ)还原菌与Fe(Ⅲ)氧化物直接接触机制、电子穿梭体的作用机制、铁载体作用机制,多种膜蛋白特别是多血红素的细胞色素蛋白参与微生物的异化Fe(Ⅲ)还原过程,并形成复杂的调控网络。此外,本文也对异化Fe(Ⅲ)还原酶促反应及其分子调控机理将来的研究方向进行了展望,以期对这一重要的生化过程有更为全面的认识。
Dissimilatory Fe（Ⅲ）-reducing bacteria are spread throughout the domain of bacteria and archaea. They are phylogenetically diverse and have been isolated under various environment conditions. Unlike other electron acceptors, Fe （Ⅲ） has a very low solubility and exists primarily as insoluble Fe oxide under neutral pH. At present, the mechanisms of gathering and reducing Fe （Ⅲ） are still poorly understood. Taking Shewanella and Geobacter as examples, this paper reviewed three kinds of possible mechanisms of microbial enzyme-catalyzed dissimilatory Fe （Ⅲ） reduction and its molecular regulation, i. e. , direct contact between microbial cell and Fe （Ⅲ） oxides, siderrophores, and electron shuttling compounds.Many membrane-bound cytochrome proteins are involved in the dissimilatory Fe （Ⅲ） reduction, forming a complicated regulation network. This paper also proposed future research directions on the mechanisms of enzyme-catalyzed dissimilatory Fe （Ⅲ） reduction so as to better understand this important biochemical process.
出处
《生态学杂志》
CAS
CSCD
北大核心
2009年第7期1381-1387,共7页
Chinese Journal of Ecology
基金
国家自然科学基金项目(20807059)
重庆大学青年骨干教师创新能力培育基金资助项目(CDCX025)
关键词
异化Fe(Ⅲ)还原菌
异化Fe(Ⅲ)还原机制
电子受体
分子调控
dissimilatory Fe （Ⅲ）-reducing bacteria
mechanisms of dissimilatory Fe （Ⅲ） reduction
electron acceptor
molecular regulation.
