氟比洛芬脂超前镇痛预防瑞芬太尼麻醉后痛觉过敏被引量：24

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摘要目的:观察氟比洛芬脂超前镇痛预防瑞芬太尼麻醉后痛觉过敏的疗效与不良反应。方法:选择腹腔镜下行胆囊切除术患者60例,ASAⅠ～Ⅱ级,分为A、B、C组,每组20例。A组在麻醉诱导后5min静脉注入氟比洛芬脂75mg,B组在麻醉结束拔管后5min静脉注入氟比洛芬脂75mg,C组在麻醉结束拔管后5min静脉注入生理盐水10mL。观察记录3组患者术后15min、1h、2h、4h、8h各时段疼痛评分,同时记录3组拔管期间躁动和呛咳的发生率,术后8h内有无嗜睡、恶心呕吐等不良反应。结果:A组患者在术后4h内不同时段疼痛评分明显低于C组(P﹤0.05),且A组在术后1h内的疼痛评分明显低于B组(P﹤0.05),A组拔管期间躁动和呛咳的发生率明显低于B组和C组(P﹤0.05)。结论:氟比洛芬脂超前镇痛可减轻瑞芬太尼麻醉后痛觉过敏,明显缓解腔镜手术患者的早期疼痛,降低拔管期间躁动和呛咳的发生率。

作者秦钟姚敏艾青

机构地区江苏省无锡市人民医院麻醉科

出处《实用医学杂志》 CAS 北大核心 2009年第11期1887-1888,共2页 The Journal of Practical Medicine

关键词痛觉过敏氟比洛芬脂超前镇痛瑞芬太尼

分类号 R614 [医药卫生—麻醉学]

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