摘要
目的探讨卒中后痴呆发生率及其危险因素。方法对403例脑梗死患者进行3个月随访评价，包括一般情况、血管性危险因素、卒中特性及神经病学体征，对痴呆组与非痴呆组中分类变量用x2检验，定量变量用t检验，筛选出痴呆相关因素后进行多因素logistic回归模型分析。结果．脑梗死3个月后403例患者中发生卒中后痴呆87例，发生率为21．6％。其主要危险因素为年龄（OR=1．179，95％CI=1．130～1．230）、低教育水平（OR：1．806，95％CI=1．024～3．186）、每日饮酒（OR=3．447，95％CI=1．591～7．468）、有卒中史（OR：2．531，95％CI=1．419～4．512）、心房纤颤（OR=3．475，95％CI=1．712～7．057）、言语障碍（OR=5．873，95％CI=2．620～13．163）及左颈动脉梗塞（OR=1．975，95％CI—1．152～3．388）等。结论卒中后痴呆发生率是由多种危险因素综合作用决定的，言语障碍是最重要的影响因素。
Objective To identify the frequency and risk factors of vascular dementia. Methods A total of 403 consecutive patients with ischemic stroke were evaluated during admission and 3 months after strok in this study,the demographic data,vascular risk factors, stroke features, and neurological status information were collected, the data were compared with 2 test or t test, Logis- tic regression analysis was used to find the risk factors of vascular dementia. Results The frequency of vascular dementia was 21.6% ,the risk factors included age （OR-1. 179,95%CI= 1. 130--1. 230） ,low educational level（OR= 1. 806,95 % CI= 1. 024-- 3. 186）,everyday drinking（OR= 3. 447,95 %CI= 1. 591--7. 468）,prior stroke（OR= 2. 531,95%CI= 1. 419--4. 512）,atrial fibrilla- tion（OR= 3. 475,95 % CI= 1. 712 -- 7. 057）, dysphasia（OR = 5. 873,95 % cI= 2. 620 - 13. 163）, and left carotid territory infarction （OR=I. 975,95%CI=1. 152--3. 388）. Conclusion The frequency of vascular dementia is affected by multiple factors such as dys- phasia, everyday drinking, atrial fibrillation, prior stroke, low educational level,left carotid territory infarction, and age, etc. Dyspha- sia are the most important influence factor.
出处
《重庆医学》
CAS
CSCD
北大核心
2009年第11期1316-1318,共3页
Chongqing medicine
