摘要
目的观察长期蚊香熏染环境对小鼠学习记忆能力的影响。方法将经过筛选后智力水平接近的20只小鼠随机分为蚊香组和对照组,每组10只。蚊香组每天置于蚊香环境中8h,对照组正常饲养。7天后,对2组小鼠进行避暗实验,记录、比较停止熏染后0h、24h、48h各组小鼠的潜伏期和错误次数。结果停止熏染蚊香后0h,蚊香组小鼠错误次数比对照组多,潜伏期较之缩短(P<0.05或P<0.01);停熏后24h和48h两组间各指标差异无统计学意义(P>0.05)。结论长期使用蚊香会妨碍小鼠短时间内学习记忆的能力,而对长时学习记忆能力影响不明显。
Objective To investigate the effects of long - term use of mosquito -repellent incense coils on the learning and memory in mice. Methods 20 mice with similar intelligence were selected by intellectual screening from 40 mice and were randomly divided into 2 groups： mosquito - repellent incense group and the control group （n = 10 each）. Mice in mosquito - repellent incense group were subjected to the environment of burning mosquito - repellent incense coils for 8 h per day, while the animals in the control group were reared in normal conditions. 7 days later, step - through tests were conducted on mice in both groups. The latencies and the numbers of errors at such time points as 0 h, 24 h and 48 h after incensing were noted and compared. Results At 0 h after incensing, the numbers of errors increased and the lateneies shortened as compared to the control group （ P 〈 0.05, P 〈 0.01 ）. However, the parameters at 24 h and 48 h between the two groups had no statistical significance （ P 〉 0.05 ）. Conclusion Long - term use of mosquito - repellent incense coils can hinder the learning and memory abilities in mice within a short period of time, while there was no evident inhibition to the longterm learning and memory.
出处
《徐州医学院学报》
CAS
2009年第5期321-322,共2页
Acta Academiae Medicinae Xuzhou
基金
江苏省高校自然科学基础研究项目(07KJD310219)
关键词
蚊香
拟除虫菊酯
学习记忆
避暗实验
mosquito - repellent incense coils
pyrethroids
learning and memory
step - through test
