摘要
目的:探讨血清TNF-α与原发性高血压的关系。方法:选取我院门诊及住院的原发性高血压患者142例及同期我院健康体检人员126例,采用酶联免疫吸附法测定血清TNF-α浓度,行血清TNF-α与血压水平的相关研究。结果:清除体重指数与血清总胆固醇水平对血清TNF-α水平的影响后,高血压人群血清TNF-α水平均明显高于血压正常人群,且血清TNF-α水平与血压水平呈正相关。结论:血清TNF-α可能参与了原发性高血压的发生、发展。
Objective： to investigate the relationship between level of plasma TNF-α and blood pressure. Methods： 142 hypertensives and 126 normotensives were chosen from the first hospital of Yu Lin city. After adjusted for body mass index and Total Cholesterol, the comparison of serum TNF-α level was carried out between hypertensives and homotensives. Results ：The findings show that after adjusted for body mass index and Total Cholesterol, the level of serum TNF -α in hypertensives was significant higher than that in nomotensives; the level of serum TNF -α was increased with blood pressure. Conclusion： Serum TNF -α may be involved into the development of hypertension.
出处
《农垦医学》
2009年第1期13-15,共3页
Journal of Nongken Medicine
