摘要
总结近几年来关于中医药治疗实验性自身免疫性脑脊髓炎(EAE)的文献,发现某些中药有效成分及复方具有能够减轻EAE病情,改善神经功能评分,抑制脑和脊髓炎症反应和脱髓鞘改变,调节中枢神经系统的免疫功能。但EAE模型制备在实验动物、抗原种类及剂量、佐剂等方面的选择上存在较大差异。
This article summarizes the researches on prevention and treatment for experimental autoimmune encephalomyelitis （ EAE ） by traditional Chinese medicine in recent years. It is found that some active components and formulae can reduce EAE disease, improve neurological score, inhibit the inflammation and demyelination in the brain and spinal cord, and regulate immune function in central nervous system. However, there are many differences in experimental animals, the type and dose of antigens and adjuvants in inducing EAE model.
出处
《上海中医药杂志》
2009年第4期83-84,F0003,共3页
Shanghai Journal of Traditional Chinese Medicine
基金
国家自然基金资助项目(30873230)
北京市自然基金资助项目(7092014)
北京市教育委员会科技发展计划项目(KM200710025015)
国家中医药管理局留学回国人员科技活动择优资助项目(国中医药研2006LHR16)
关键词
实验性自身免疫性脑脊髓炎
中医药
综述
Experimental autoimmune encephalomyelitis
traditional Chinese medicine
review
