摘要
目的观察熊去氧胆酸联合多烯磷脂酰胆碱治疗非酒精性脂肪性肝炎的疗效。方法将82例非酒精性脂肪性肝炎(NASH)随机分为治疗组40例和对照组42例,治疗组用熊去氧胆加多烯酯磷脂酰碱治疗,对照组单用多烯酯磷脂酰碱治疗,疗程均为6个月。结果治疗组症状、肝功能、血脂、B超检查结果改善均优于对照组,两组疗效比较差异有统计学意义(P<0.05)。结论熊去氧胆酸联合多烯磷脂酰胆碱治疗非酒精性脂肪性肝炎疗效好。
Objective To observe the clinical effect of ursodeoxycholic acid (UDCA) combined with polyene phosphatidyleholin in treating non-alcohdic steatohepatitis (NASH). Methods 82 patients with nonalcoholic steatohepatitis were randomly divided into the treated group ( n = 40, treated with UDCA and polyene phosphatidyleholin in combination) and the control group ( n = 42, treated with polyene phosphatidylcholin alone). The therapeutic course lasted 6 months. Results The improvement of syndrome,liver function,blood lipid and B ultrasonic figure in the treated group was superior to that in the control group, and the clinical effieacies between the two groups were significantly different(P 〈 0. 05 ). Conclusion UDCA combined with polyene phosphatidylcholin has a good effect in treating NASH.
出处
《中国实用医药》
2009年第10期11-12,共2页
China Practical Medicine
关键词
非酒精性脂肪性肝炎
多烯磷脂酰胆碱
熊去氧胆酸
Non-alcoholic fatty hepatitis
Polyene phosphatidylcholin
Ursodeoxycholic acid