摘要
目的:探讨重症加强治疗病房(ICU)鲍曼不动杆菌耐药性特点及其与中医证候的关系。方法:分离ICU住院患者中124株鲍曼不动杆菌,采用K-B纸片扩散法进行体外药敏试验,分析鲍曼不动杆菌感染及与中医证候的关系。结果:除阿米卡星外(敏感率为52.42%),124株鲍曼不动杆菌对多种抗菌药物耐药(敏感率<30.00%)。鲍曼不动杆菌感染者的中医证候以虚实夹杂证为主,虚实夹杂证的各证中以痰阻证(65.3%)、阴虚证(61.9%)、气虚证(55.9%)、热郁证(53.4%)为主。结论:对多重耐药鲍曼不动杆菌感染的患者应以亚胺培南作为一线抗菌药物,同时可考虑采用中医辨证论治辅助治疗。
Objective ：To assess the relationship between the characteristic of drug resistance in Acinetobacter baumannii and the syndrome of traditional Chinese medicine （TCM） in intensive care unit （ICU）. Methods ： 124 strains of Acinetobacter baumannii were isolated from sputum specimens of patients in our ICU from March 2007 to February 2008. The data of the drug sensi- tivity test in vitro was analyzed. The relation between the syndrome of TCM and drug resistance in Acinetobacter baumannii was probed. Results ：The 124 strains of Acinetobacter baumannii were drug resistant to multiple kinds of anti-bacterial drugs （ sensitivi- ty rate 〈 30. 00% ） except amikacin （ sensitivity rate 52. 42% ）. The syndromes of TCM of all patients infected mainly with Acine- tobacter bamnannii were vacuity-repletion complex. The main TCM syndromes were phlegm obstruction （ 65.3% ）, Yin vacuity （ 61.9% ）, Qi vacuity（55.9% ）, Heat depression（ 53.4% ）. Concision ： Imipenem is the first line anti-bacterial drug to be select- ed for the treatment of cases infected with Acinetobacter baumannii with multiple drug resistance. In the mean time, identifying patterns of various syndromes in TCM to determine the Chinese medicinal drug treatment for help might be considered for such patient＇s treatment.
出处
《辽宁中医杂志》
CAS
北大核心
2009年第4期499-500,共2页
Liaoning Journal of Traditional Chinese Medicine
关键词
鲍曼不动杆菌
耐药性
中医证候
Acinetobacter baumannii
drug resistance
syndrome of traditional Chinese medicine
