摘要
目的:对中草药治疗腹泻型肠易激综合征的临床疗效和安全性进行系统评价。方法:通过计算机检索全面收集国内外有关中草药治疗腹泻型肠易激综合征的随机/半随机对照试验。共纳入163篇文献,包括14150例病人,其中样本量(包括治疗组和对照组)最大为234例,最小的为40例,平均87例。因干预措施复杂多样,仅进行定性分析。结果:中药干预有明显疗效,其痊愈率为(50.80±24.70)%,总有效率为(90.68±7.30)%,优于西药干预的(28.85±17.77)%及(71.07±11.38)%,其复发率(18.99±10.61)%也明显低于西药干预组(52.25±18.42)%;对腹痛、腹胀、腹泻三大主要症状的疗效也优于西药干预组。结论:中草药治疗腹泻型肠易激综合征有明显疗效,在总体症状痊愈率、总有效率、症状积分改善及复发方面均优于西药干预及安慰剂组,且未发现严重不良反应。
Objective： To assess the e cacy and safety of treating D-IBS with Chinese herbal medicine. Methods： To collect comprehensively the RCTs of treating D-IBS with Chinese herbal medicine by computer search. Results： Up to Nov. 2007, one hundred and sixty-three trials were included. There have 14150 patients, the maximum sample number is 234, the minimum is 40, and the average sample is 87. Because of the complex and various interventions, we just do descriptive analysis. It indicated that the Chinese herbal medicine intervention has obvious e cacy, its cure rate was（50.80±24.70）%,total e ective rate was（90.68±7.30）%and recurrence rate was（18.99±10.61）% all better than the western medicine. Conclusion： Compared with the western medicine and placebo, the Chinese herbal medicine had obvious e cacy in improving the global symptom’s cure rate, total e ective rate, symptom score and recurrence rate, and didn’t discovery seriously adverse reaction.
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2009年第4期532-535,共4页
China Journal of Traditional Chinese Medicine and Pharmacy
基金
北京市科委基金(No.Z0005190043711)
首都发展基金资助(No.SF-2005-9)
关键词
肠易激综合征
腹泻型
中草药治疗
系统评价
Irritable bowel syndrome
Diarrhea-predominant pattern
Chinese herbal medicine
Systematic review
