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继发孔房间隔缺损3种治疗技术的对比研究 被引量:19

Comparison study of mini-invasive surgery,transcatheter closure and open-heart surgery for treatment of Secundum Atrial Septal Defect
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摘要 目的:对外科微创封堵、导管介入封堵与体外循环直视修补术3种治疗继发孔房间隔缺损(ASD)的技术进行回顾性对比研究。方法:2006年1月至12月,116例继发孔ASD患者分别接受了外科微创封堵术(A组)、导管介入封堵术(B组)与体外循环直视修补术(C组)的治疗。结果:3组患者均无围术期死亡病例。C组在手术时间,总出血量和术后住院天数等方面均要明显大于A组和B组,后2组间则无明显差异。术后带气管插管时间,C组明显大于A组。住院费用方面,B组要明显高于A组和C组,而后2组间则无明显差异。结论:3种技术均是治疗继发孔ASD的有效方法。外科微创封堵术适应症广、无X线辐射、术后恢复快、住院时间短、费用低及疗效可靠;而且操作简单并利于推广。在很大程度上要优于体外循环直视修补术和导管介入封堵术。 Objective:In this retrospective study, we compared three different procedures, including mini- invasive surgery, transcatheter closure and open-heart surgery, to analyze which technique is possibly the best option for treatment of secundum atrial septal defect. Method: 116 patients were enrolled in this study. Specifically 21 patients were treated by minl-invasive surgery (group A), 26 by transeatbeter closure (group B) and 69 by traditional open-heart surgery (group C). The mean age of three groups was 33.7 ± 13.8, 27.1 ±15.6 and (31.8 ± 14.8) years old respectively. Meanwhile the diameters of atrial septal defect were 23.0 ± 7.9, 18.3 ±6.8 and (26.5 ± 7.8) ram, respectively. Result: There was no perioperative death in each group. The success rate of treatment was 95.2 % for group A, 92.3% for group B and 100% for group C. Residual shunt incidence of three groups were 0% and 3.8% and 0% respectively. The mean operation time, bleeding and length of hospital stay of group C was significantly higher than group A and group B, but there was no significant difference between group A and group B as far as these three indexes are concerned. The duration of postoperative ventilation of group C was significantly longer than group A. The cost of group B was higher than group A and group C. Conclusion: The three procedures were all effective for treating secundum atrial septal defect. However, the Mini-invasive surgery is more superior to the other two techniques in terms of wide indications, simplicity, radiation damage, recovering, and outcomes.
出处 《心肺血管病杂志》 CAS 2009年第1期14-17,共4页 Journal of Cardiovascular and Pulmonary Diseases
关键词 房间隔缺损 外科微创封堵术 导管介入封堵 体外循环直视修补术 Secundum atrial septal defect Heart surgery Transcatheter Mini-invasive operation Occlusion
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