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B型尿钠肽和氨基末端B型尿钠肽前体在心血管疾病的研究进展 被引量：5

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摘要 目前，B型尿钠肽（BNP）和氨基末端BNP前体（NT-proBNP）的检测已逐渐应用于临床，其水平与疾病的严重程度和心力衰竭（HF）的预后，以及HF患者对治疗的反应密切相关。近年研究认为，NT-proBNP对于诊断轻度HF或无症状左心室功能不全似乎更具优势。我们就两者在心血管疾病中各自的临床意义作一综述。
作者 赵茹 刘寅
机构地区 天津市胸科医院心血管内科
出处 《中华老年心脑血管病杂志》 CAS 北大核心 2009年第3期237-238,共2页 Chinese Journal of Geriatric Heart,Brain and Vessel Diseases
关键词 利钠肽 脑 心力衰竭 充血性
分类号 R54 [医药卫生—心血管疾病] R541.6 [医药卫生—心血管疾病]
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参考文献13

  • 1Martinez-Rumayor A, Richards AM, Burnett JC, et al. Biology of the natriuretic peptides. Am J Cardiol, 2008,101 : 3A-8A.
  • 2Masson S, Latini R, Anand IS, et al. Direct comparison of B- type natriuretic peptide(BNP) and amino terminal proBNP in a large population ot patients with chronic and symptomatic heart failure: the Valsartan Heart Failure(Val-HeFT) data. Clin Chem, 2006,52: 1528-1538.
  • 3Mair J, Gerda F, Renate H, et al. Head-to-head comparison of B type natriuretic peptide (BNP) and NT-proBNP in daily clinical practice. Int J Cardiol, 2008,124: 244-246.
  • 4Anwaruddin S, Llotd-Jones DM, Baggish A, et al. Renal funetion, congestive heart failure, and amino-terminal pro-brain natriuretic peptide measurement= results from the ProBNP Investigation of Dyspnea in the Emergency Department (PRIDE)Study. J Am Coll Cardiol,2006,47:91-97.
  • 5Kroll MH,Srisawasdi P. The clearance of BNP modeled using the NT-proBNP/BNP relationship. Biosystems, 2007,88:147- 155.
  • 6Guglin M, Hourani R, Pitta S. Factors determining extreme brain natriuretic peptide elevation. Congest Heart Fail,2007, 13:136-141.
  • 7Hogenhuis J ,Voors AA,Jaarsma T, et al. Anaemia and renal dysfunction are independently associated with BNP and NT proBNP levels in patients with heart failure. Eur J Heart Fail, 2007,9:787-794.
  • 8Mueller C, Breidthardt T, Laule Kilian K, et al. The integration of BNP anf NT-proBNP into clinical medicine. Swiss Med Wkly,2007,137:4-12.
  • 9缪海雄,夏向南.脑利钠肽在老年舒张性心力衰竭与收缩性心力衰竭中的对比分析[J].中华老年心脑血管病杂志,2008,10(6):461-461. 被引量：3
  • 10McKie PM, Rodeheffer RJ ,Cataliotti A, et al. Amino terminal pro-B-type natriuretic peptide and B-type natriuretic peptide: hiomarkers for mortality in a large community based cohort free of heart failure. Hypertension, 2006,47:874-880.

二级参考文献3

  • 1Clerico A,Fontana M,Zyw L,et al. Comparison of the diagnostic accuracy of brain natriuretic peptide (BNP) and the N-terminal part of the polypeptide of BNP immunoassays in chronic and acute heart failure: A systematic review. Clin Chem, 2007, 53:813-822.
  • 2Swedberg K, Cleland J, Drexler H, et al. Task Froce for the Diagnosis and Treatment of Chronic Heart Failure of the European Society of Cardiology. Guidelines for the diagnosis and treatment of chronic heart failure: executive summary (update 2005). Eur Heart J,2005,26:1115-1140.
  • 3Abdullah SM,Khera A,Das SR,et al. Relation of coronary atherosclerosis determined by electron beam computed tomography and plasma levels of N terminal pro-brain natriuretic peptide in a multiethnic population-based sample (The Dallas Heart Study). Am J Cardiol, 2005,96 : 1284-1289.

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同被引文献41

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二级引证文献11

中华老年心脑血管病杂志
2009年 第3期

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