摘要
应用激光多普勒测定微血管血流灌注技术,观察体外反搏提高灌注压力对失血性休克犬大脑皮层及皮肤微血管血流灌注的作用。结果显示,体外反搏可明显提高休克犬主动脉平均压力,增加休克犬大脑皮层及皮肤微血管血流灌注。在回输失血复苏后,对照组和反搏组主动脉平均压力恢复接近失血前水平,但反搏组微血管灌注的回升却明显高于对照组。结果提示体外反搏在犬失血性休克期预处理能改善其微循环障碍。
Effect of external counterpulsation(ECP) on cerebral and skin microvascular perfusion were observed in hemorhagic shock canines with Laser Doppler Flowmeter technique. ECP augmented mean aortic pressure and increased cerebral and skin microvascular perfusion obviously in hemorhagic shock canines. After administering all shed blood, though the mean aortic pressures of control and ECP groups were recovered nearly to the basic level, the increase of microvascular perfusion in ECP groups was higher significantly than that in control groups. The results indicated that pre-treatment with ECP during the shock period could improve microcirculatory disorder effectively and then be beneficial to microvascular perfusion during the resuscitation.
出处
《微循环学杂志》
1998年第1期8-10,共3页
Chinese Journal of Microcirculation
基金
国家自然科学基金资助