摘要
目的探讨风湿性二尖瓣狭窄(MS)患者二尖瓣环运动速率与二尖瓣置换术术后恢复情况的相关性。方法44例接受二尖瓣置换术的风湿性单纯MS患者分为恢复良组和恢复差组,术前、术后多普勒组织成像(DTI)技术检测二尖瓣环射血期、舒张早期峰值速率Vs、Ve;术中取乳头肌组织行心肌病理学检查。比较两组间各指标的差异。结果术前、术后平均Vs和术前平均Ve均表现为恢复良组显著大于恢复差组,恢复差组心肌纤维化比例显著高于恢复良组,余指标组间无显著性差异。结论单纯MS时二尖瓣置换术术后恢复情况与二尖瓣环速率、心肌纤维化程度相关,提示DTI可用于无创判断二尖瓣置换术预后。
AIM To investigate the correlation between the peak velocities of mitral annuli during systole and diastole and the recovery of patients with rheumatic mitral stenoses （MS） after operation of mitral valve （MV） replacement. METHODS Forty-four patients with pure rheumatic MS undergoing MV replacement were divided into good recovery group and poor recovery group. Specimens of papillary muscles were collected during operations for pathological analyses. Vs, the mean of peak velocity of mitral annulus during ejection phase and Ve, the mean of peak velocity of mitral annulus during early diastolic phases were measured by Doppler tissue imaging （DTI） before and after MV replacement. All the measurements were compared between the two groups. RESULTS Vs before and after MV replacement and Ve before MV replacement in the good recovery group were significantly larger than those in the poor recovery group. Ratio of fibrous tissue to myocardia was significantly larger in the poor recovery group compared with that in the fine recovery group. No statistical differences in other measurements was found between the two groups. CONCLUSION Association between recovery and DTI measurements and between recovery and myocardial fibrosis are found, which suggests that velocities of mitral annulus measured by DTI can be used to estimate noninvasively the prognoses of patients undergoing MV replacements.
出处
《心脏杂志》
CAS
2009年第1期85-87,共3页
Chinese Heart Journal
