摘要
目的观察美托洛尔联用卡托普利治疗慢性心力衰竭的疗效和安全性。方法90例慢性心力衰竭病员随机分成两组。45例对照组常规用药治疗(强心、利尿及扩血管),45例治疗组在常规治疗基础上加用美托洛尔(6.25mg,2次/d,每一周增量1倍)和卡托普利(6.25～12.5mg,3次/d),疗程8周。观察治疗前后临床指标变化。结果治疗组和对照组有效率分别为91.1%和64.4%,两组比较有显著性差异(P<0.05),美托洛尔联用卡托普利组发生不良反应较少。结论美托洛尔联用卡托普利治疗慢性心力衰竭有较好的临床疗效和很少的副作用。
Objective To observe the effect and security of metoprolol combined with captopril on chronic heart failure. Methods 90 cases with chronic heart failure were randomly divided into two groups. 45 patients control group received conventional treatment （cardiotonic, diuretics and vasodilator）. 45 patients of treatment group were given metoprolol（6.25mg bid. po. add 6.25mg every week） and captopril （6.25 - 12.5mg tid.po） add conventional trealment. The clinical characteristics were observed before and after 8 weeks treatment. Results After 8 weeks,the rate of efficacy in the treatment group and control group were 91.1% and 64.4%. The averse effects of Metoprolol and Capopril were less. There were significant difference between two groups（P〈 0.05）. Conclusion Metoprolol and capopril has good result and on chronic heart failure.
出处
《中国现代医生》
2009年第4期88-89,共2页
China Modern Doctor
